Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters -: Part I.: Regioselective hydrogenation of stigmasterol:: An easy access to oxyphytosterols

被引：7

作者：

Geoffroy, Philippe ^{[1
]}

Julien-David, Diane ^{[2
]}

Marchioni, Eric ^{[2
]}

Raul, Francis ^{[3
]}

Aoude-Werner, Dalal ^{[4
]}

Miesch, Michel ^{[1
]}

机构：

[1] Univ Strasbourg 1, Inst Chim, CNRS, Lab Chim Organ Synthet,UMR 7177, F-67008 Strasbourg, France

[2] Univ Strasbourg 1, Lab Chim Analyt & Sci Aliment, CNRS, IPHC,UMR 7178,Fac Pharm, F-67401 Illkirch Graffenstaden, France

[3] Univ Strasbourg 1, INSERM, IRCAD, U682, F-67091 Strasbourg, France

[4] Aerial, F-67412 Illkirch Graffenstaden, France

来源：

STEROIDS | 2008年 / 73卷 / 07期

关键词：

hydrogenation; Nickel-Raney catalyst; regioselectivity; epoxydes; bromohydrins;

D O I：

10.1016/j.steroids.2008.02.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of several oxyphytosterols is described starting from stigmasterol, the key step being the regioselective hydrogenation of the 22-23 double bond of the latter. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：702 / 707

页数：6

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