Strategies for the systematic sequencing of complex genomes

被引：87

作者：

Green, ED ^{[1
]}

机构：

[1] NHGRI, Genome Technol Branch, NIH, Bethesda, MD 20892 USA

[2] NHGRI, Intramural Sequencing Ctr, NIH, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS GENETICS | 2001年 / 2卷 / 08期

关键词：

D O I：

10.1038/35084503

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Recent spectacular advances in the technologies and strategies for DNA sequencing have profoundly accelerated the detailed analysis of genomes from myriad organisms. The past few years alone have seen the publication of near-complete or draft versions of the genome sequence of several well-studied, multicellular organisms - most notably, the human. As well as providing data of fundamental biological significance, these landmark accomplishments have yielded important strategic insights that are guiding current and future genome-sequencing projects.

引用

页码：573 / 583

页数：11

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