Molecular evolutionary and antigenic characteristics of newly isolated H9N2 avian influenza viruses in Guangdong province, China

被引：6

作者：

Zhang, Jipei ^{[1
]}

Wu, Huiji ^{[1
]}

Zhang, Yishan ^{[1
]}

Cao, Mengrui ^{[1
]}

Brisse, Morgan ^{[2
]}

Zhu, Wanjun ^{[1
,2
]}

Li, Rongxu ^{[1
]}

Liu, Minfang ^{[1
]}

Cai, Mingsheng ^{[3
]}

Chen, Jianhong ^{[1
]}

Chen, Jidang ^{[1
]}

机构：

[1] Foshan Univ, Sch Life Sci & Engn, Foshan 528000, Guangdong, Peoples R China

[2] Univ Minnesota, Coll Vet Med, Twin Cites Campus, St Paul, MN 55108 USA

[3] Guangzhou Med Univ, Dept Pathogen Biol & Immunol, Sino French Hoffmann Inst, Sch Basic Med Sci, Guangzhou 511436, Guangdong, Peoples R China

来源：

ARCHIVES OF VIROLOGY | 2019年 / 164卷 / 02期

基金：

中国国家自然科学基金;

关键词：

INTERNAL GENES; HUMAN INFECTION; A VIRUSES; PATHOGENICITY; GENOTYPE; POULTRY;

D O I：

10.1007/s00705-018-4103-4

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Four new H9N2 avian influenza viruses (AIVs) were isolated from domestic birds in Guangdong between December 2015 and April 2016. Nucleotide sequence comparisons indicated that most of the internal genes of these four strains were highly similar to those of human H7N9 viruses. Amino acid substitutions and deletions found in the HA and NA proteins indicated that all four of these new isolates may have an enhanced ability to infect humans and other mammals. A cross-hemagglutinin-inhibition assay, conducted with two vaccine strains that are broadly used in China, suggested that antisera against vaccine candidates could not provide complete inhibition of the new isolates.

引用

页码：607 / 612

页数：6

共 33 条

[1] A review of avian influenza in different bird species [J].

Alexander, DJ .

VETERINARY MICROBIOLOGY, 2000, 74 (1-2) :3-13

[2] PERSISTENT ANTIGENIC VARIATION OF INFLUENZA A VIRUSES AFTER INCOMPLETE NEUTRALIZATION IN OVO WITH HETEROLOGOUS IMMUNE SERUM [J].

ARCHETTI, I ;

HORSFALL, FL .

JOURNAL OF EXPERIMENTAL MEDICINE, 1950, 92 (05) :441-462

[3] Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection : a descriptive study [J].

Chen, HaiYing ;

Yuan, Hui ;

Gao, Rongbao ;

Zhang, Jinxiang ;

Wang, Dayan ;

Xiong, Ying ;

Fan, GuoYin ;

Yang, Fan ;

Li, Xiaodan ;

Zhou, Jianfang ;

Zou, Shumei ;

Yang, Lei ;

Chen, Tao ;

Dong, Libo ;

Bo, Hong ;

Zhao, Xiang ;

Zhang, Ye ;

Lan, Yu ;

Bai, Tian ;

Dong, Jie ;

Li, Qun ;

Wang, ShiWen ;

Zhang, YanPing ;

Li, Hui ;

Gong, Tian ;

Shi, Yong ;

Ni, Xiansheng ;

Li, Jianxiong ;

Zhou, Jun ;

Fan, Jiyi ;

Wu, Jingwen ;

Zhou, Xianfeng ;

Hu, Maohong ;

Wan, Jianguo ;

Yang, WeiZhong ;

Li, DeXin ;

Wu, Guizhen ;

Feng, ZiJian ;

Gao, George F. ;

Wang, Yu ;

Jin, Qi ;

Liu, Mingbin ;

Shu, Yuelong .

LANCET, 2014, 383 (9918) :714-721

[4] First genome report and analysis of chicken H7N9 influenza viruses with poly-basic amino acids insertion in the hemagglutinin cleavage site [J].

Chen, Jidang ;

Zhang, Jipei ;

Zhu, Wanjun ;

Zhang, Yishan ;

Tan, Hualong ;

Liu, Minfang ;

Cai, Mingsheng ;

Shen, Jiaren ;

Hinh Ly ;

Chen, Jianhong .

SCIENTIFIC REPORTS, 2017, 7

[5] Live poultry market workers are susceptible to both avian and swine influenza viruses, Guangdong Province, China [J].

Chen, Jidang ;

Ma, Jun ;

White, Sarah K. ;

Cao, Zhenpeng ;

Zhen, Yun ;

He, Shuyi ;

Zhu, Wanjun ;

Ke, Changwen ;

Zhang, Yongbiao ;

Su, Shuo ;

Zhang, Guihong .

VETERINARY MICROBIOLOGY, 2015, 181 (3-4) :230-235

[6] In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity [J].

Chen, Li-Mei ;

Blixt, Ola ;

Stevens, James ;

Lipatov, Aleksandr S. ;

Davis, Charles T. ;

Collins, Brian E. ;

Cox, Nancy J. ;

Paulson, James C. ;

Donis, Ruben O. .

VIROLOGY, 2012, 422 (01) :105-113

[7]

Chinese Center for Disease Control and Prevention National influenza & avian-human influenza surveillance implementation plan, 2005, CHINESE CTR DIS CONT

[8] Characterization of H9N2 avian influenza viruses from the Middle East demonstrates heterogeneity at amino acid position 226 in the hemagglutinin and potential for transmission to mammals [J].

Chrzastek, Klaudia ;

Lee, Dong-hun ;

Gharaibeh, Saad ;

Zsak, Aniko ;

Kapczynski, Darrell R. .

VIROLOGY, 2018, 518 :195-201

[9] Antigenic and genetic characterization of H9N2 swine influenza viruses in China [J].

Cong, Yan L. ;

Pu, Juan ;

Liu, Oin F. ;

Wang, Shuai ;

Zhang, Guo Z. ;

Zhang, Xing L. ;

Fan, Wei X. ;

Brown, Earl G. ;

Liu, Jin H. .

JOURNAL OF GENERAL VIROLOGY, 2007, 88 :2035-2041

[10] Human-Animal Interface: The Case for Influenza Interspecies Transmission [J].

Donatelli, Isabella ;

Castrucci, Maria R. ;

De Marco, Maria A. ;

Delogu, Mauro ;

Webster, Robert G. .

EMERGING AND RE-EMERGING VIRAL INFECTIONS: ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH, VOL 6, 2017, 972 :17-33

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