Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant

被引:1
作者
van der Velden, Fabian J. S. [1 ,2 ]
van Delft, Frederik [3 ]
Owens, Stephen [1 ]
Llevadias, Judit [4 ]
McKean, Michael [5 ]
Pulford, Lindsey [4 ]
Taha, Yusri [6 ]
Williamson, Grace [7 ]
Campbell-Hewson, Quentin [3 ]
Hambleton, Sophie [1 ,2 ]
Payne, Rebecca [2 ]
Duncan, Christopher [2 ,8 ]
Johnston, Catriona [9 ]
Spegarova, Jarmila [2 ]
Emonts, Marieke [1 ,2 ]
机构
[1] Great North Childrens Hosp, Newcastle Tyne Hosp NHS Fdn Trust, Paediat Immunol Infect Dis & Allergy, Newcastle Upon Tyne, Northumberland, England
[2] Newcastle Univ, Translat & Clin Res Inst, Fac Med Sci, Newcastle Upon Tyne, Northumberland, England
[3] Great North Childrens Hosp, Newcastle Tyne Hosp NHS Fdn Trust, Paediat Oncol, Newcastle Upon Tyne, Northumberland, England
[4] Newcastle Tyne Hosp NHS Fdn Trust, Freeman Hosp, Paediat Intens Care, Newcastle Upon Tyne, Northumberland, England
[5] Great North Childrens Hosp, Newcastle Tyne Hosp NHS Fdn Trust, Paediat Resp Dept, Newcastle Upon Tyne, Tyne & Wear, England
[6] Newcastle Tyne Hosp NHS Fdn Trust, Virol, Newcastle Upon Tyne, Northumberland, England
[7] Great North Childrens Hosp, Newcastle Upon Tyne Hosp NHS Fdn Trust, Paediat Intens Care, Newcastle Upon Tyne, Tyne & Wear, England
[8] Newcastle Tyne Hosp NHS Fdn Trust, Infect Dis & Trop Med, Newcastle Upon Tyne, Tyne & Wear, England
[9] Newcastle Upon Tyne Hosp NHS Fdn Trust, Pharm, Newcastle Upon Tyne, Tyne & Wear, England
来源
FRONTIERS IN PEDIATRICS | 2022年 / 10卷
基金
欧盟地平线“2020”;
关键词
pediatric; COVID-19; stem cell transplant; immunomodulation; immunodeficient; ORGANIZING PNEUMONIA; ASSOCIATION; RECIPIENTS; MORTALITY;
D O I
10.3389/fped.2022.809061
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.
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收藏
页数:8
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