Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2

被引：1350

作者：

Shi, Jianzhong ^{[1
]}

Wen, Zhiyuan ^{[1
]}

Zhong, Gongxun ^{[1
]}

Yang, Huanliang ^{[1
]}

Wang, Chong ^{[1
]}

Huang, Baoying ^{[2
]}

Liu, Renqiang ^{[1
]}

He, Xijun ^{[3
]}

Shuai, Lei ^{[1
]}

Sun, Ziruo ^{[1
]}

Zhao, Yubo ^{[1
]}

Liu, Peipei ^{[2
]}

Liang, Libin ^{[1
]}

Cui, Pengfei ^{[1
]}

Wang, Jinliang ^{[1
]}

Zhang, Xianfeng ^{[3
]}

Guan, Yuntao ^{[3
]}

Tan, Wenjie ^{[2
]}

Wu, Guizhen ^{[2
]}

Chen, Hualan ^{[1
]}

Bu, Zhigao ^{[1
,3
]}

机构：

[1] Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin 150069, Peoples R China

[2] China CDC, Natl Inst Viral Dis Control & Prevent, Beijing 102206, Peoples R China

[3] Natl High Containment Lab Anim Dis Control & Prev, Harbin 150069, Peoples R China

来源：

SCIENCE | 2020年 / 368卷 / 6494期

关键词：

VIRUS; INFECTION; TRANSMISSION;

D O I：

10.1126/science.abb7015

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes the infectious disease COVID-19 (coronavirus disease 2019), which was first reported in Wuhan, China, in December 2019. Despite extensive efforts to control the disease, COVID-19 has now spread to more than 100 countries and caused a global pandemic. SARS-CoV-2 is thought to have originated in bats; however, the intermediate animal sources of the virus are unknown. In this study, we investigated the susceptibility of ferrets and animals in close contact with humans to SARS-CoV-2. We found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection. Additionally, cats are susceptible to airborne transmission. Our study provides insights into the animal models for SARS-CoV-2 and animal management for COVID-19 control.

引用

页码：1016 / +

页数：27

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