Electron microscopic comparison of the donor cut edges using femtosecond laser-assisted keratoplasty versus conventional keratoplasty

被引：0

作者：

Tolba, Mohamed Y. ^{[1
]}

Zaki, Iman M. A. ^{[2
]}

Raafat, Karim A. ^{[3
]}

Al Dib, Amr A. ^{[4
]}

Eleiwa, Taher ^{[5
]}

Chase, Collin ^{[6
]}

Taher, Ibrahim M. ^{[4
]}

机构：

[1] Eye Specialty Hosp, Ophthalmol Dept, Cairo, Egypt

[2] Cairo Univ, Res Inst Ophthalmol, Pathol Dept, Cairo, Egypt

[3] Cairo Univ, Fac Med, Ophthalmol Dept, Cairo, Egypt

[4] Cairo Univ, Natl Inst Laser Sci, Ophthalmol Dept, Cairo, Egypt

[5] Benha Univ, Fac Med, Ophthalmol Dept, Banha, Egypt

[6] Univ S Florida, Morsani Coll Med, Tampa, FL 33620 USA

来源：

SAUDI JOURNAL OF OPHTHALMOLOGY | 2021年 / 35卷 / 01期

关键词：

Electron microscopic study of the cornea; femtoassisted keratoplasty; penetrating keratoplasty; SHAPED PENETRATING KERATOPLASTY; CORNEAL TREPHINATION; ENDOTHELIAL KERATOPLASTY; EXCIMER-LASER; DISSECTION;

D O I：

10.4103/1319-4534.325785

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To describe and compare the histological changes in the cut edges of the remaining donor corneal rim using femtosecond laser-assisted keratoplasty (FAK) versus conventional penetrating keratoplasty (PK) via light and transmission electron microscopic examination. METHODS: This was a prospective observational study of 10 eyes; 5 FAK (top-hat technique) and 5 conventional PK. Main outcomes were histological findings at the cut edge of the donor corneal rim (at 3, 6, 9, and 12 o'clock). RESULTS: Cellular and ultra-cellular changes in the form of stromal edema, disorganized collagen fibers, and nuclear changes were more prominent in the FAK eyes as compared to the conventional PK ones. CONCLUSION: FAK induces more collateral damage in the cut edge of corneal donor graft at cellular and ultra-cellular levels, compared to conventional trephination. Further studies are required to investigate the clinical ramifications of this observation.

引用

页码：47 / 51

页数：5

共 34 条

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