Generation of Hot Spots with Silver Nanocubes for Single-Molecule Detection by Surface-Enhanced Raman Scattering

被引:265
作者
Rycenga, Matthew [1 ]
Xia, Xiaohu [1 ]
Moran, Christine H. [1 ]
Zhou, Fei [2 ]
Qin, Dong [3 ]
Li, Zhi-Yuan [2 ]
Xia, Younan [1 ]
机构
[1] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA
[2] Chinese Acad Sci, Inst Phys, Beijing 100080, Peoples R China
[3] Washington Univ, Dept Energy Environm & Chem Engn, St Louis, MO 63130 USA
基金
美国国家科学基金会;
关键词
nanostructures; silver; single-molecule detection; surface-enhanced Raman scattering; surface plasmon resonance; NANOPARTICLE; SERS; SPECTROSCOPY; DIMERS; RANGE; PROOF; FILM;
D O I
10.1002/anie.201101632
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Getting hotter: Hot spots that enable detection of surface-enhanced Raman scattering (SERS) from a single molecule can form at the nanocube-substrate interface by simply depositing a silver nanocube onto a metal substrate (see picture). This new approach offers great simplicity for the formation of robust and fully accessible hot spots, thus providing an effective platform for ultrasensitive detection. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:5473 / 5477
页数:5
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