Can the wound healing response of human skin be modulated after laser treatment and the effects of exposure extended? Implications on the combined use of the pulsed dye laser and a topical angiogenesis inhibitor for treatment of port wine stain birthmarks

被引:55
作者
Phung, Thuy L. [2 ]
Oble, Darryl A. [1 ]
Jia, Wangeun [3 ]
Benjamin, Laura E. [2 ]
Mihm, Martin C., Jr. [1 ]
Nelson, J. Stuart [3 ]
机构
[1] Harvard Univ, Sch Med, Dept Dermatol, Massachusetts Gen Hosp, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Dept Pathol, Beth Israel Deaconess Med Ctr, Boston, MA USA
[3] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92715 USA
关键词
D O I
10.1002/lsm.20599
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
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页码:1 / 5
页数:5
相关论文
共 13 条
[1]   SELECTIVE PHOTOTHERMOLYSIS - PRECISE MICROSURGERY BY SELECTIVE ABSORPTION OF PULSED RADIATION [J].
ANDERSON, RR ;
PARRISH, JA .
SCIENCE, 1983, 220 (4596) :524-527
[2]   TSC2 regulates VEGF through mTOR-dependent and -independent pathways [J].
Brugarolas, JB ;
Vazquez, F ;
Reddy, A ;
Sellers, WR ;
Kaelin, WG .
CANCER CELL, 2003, 4 (02) :147-158
[3]   Angiogenesis in life, disease and medicine [J].
Carmeliet, P .
NATURE, 2005, 438 (7070) :932-936
[4]   Angiogenesis as a therapeutic target [J].
Ferrara, N ;
Kerbel, RS .
NATURE, 2005, 438 (7070) :967-974
[5]   Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor [J].
Guba, M ;
von Breitenbuch, P ;
Steinbauer, M ;
Koehl, G ;
Flegel, S ;
Hornung, M ;
Bruns, CJ ;
Zuelke, C ;
Farkas, S ;
Anthuber, M ;
Jauch, KW ;
Geissler, EK .
NATURE MEDICINE, 2002, 8 (02) :128-135
[6]   Defining the role of mTOR in cancer [J].
Guertin, David A. ;
Sabatini, David M. .
CANCER CELL, 2007, 12 (01) :9-22
[7]   Redarkening of port-wine stains 10 years after pulsed-dye-laser treatment [J].
Huikeshoven, Menno ;
Koster, Petra H. L. ;
de Borgie, Corianne A. J. M. ;
Beek, Johan F. ;
van Gemert, Martin J. C. ;
van der Horst, Chantal M. A. M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (12) :1235-1240
[8]   Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy [J].
Jain, RK .
SCIENCE, 2005, 307 (5706) :58-62
[9]  
Lanigan SW, 1998, BRIT J DERMATOL, V139, P173
[10]   INITIAL LESION SIZE AS A PREDICTIVE FACTOR IN DETERMINING THE RESPONSE OF PORT-WINE STAINS IN CHILDREN TREATED WITH THE PULSED DYE-LASER [J].
MORELLI, JG ;
WESTON, WL ;
HUFF, JC ;
YOHN, JJ .
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1995, 149 (10) :1142-1144