Cardiac Vagus and Exercise

被引：87

作者：

Gourine, Alexander V. ^{[1
]}

Ackland, Gareth L. ^{[2
]}

机构：

[1] UCL, Ctr Cardiovasc & Metab Neurosci, Neurosci Physiol & Pharmacol, London, England

[2] Queen Mary Univ London, William Harvey Res Inst, Barts & London Sch Med & Dent, London, England

来源：

PHYSIOLOGY | 2019年 / 34卷 / 01期

基金：

英国惠康基金;

关键词：

HEART-RATE RECOVERY; VAGAL POSTGANGLIONIC INNERVATION; LEFT-VENTRICULAR CONTRACTILITY; DORSAL MOTOR NUCLEUS; ALL-CAUSE MORTALITY; AUTONOMIC FUNCTION; PHYSICAL-FITNESS; PREGANGLIONIC NEURONS; DYNAMIC EXERCISE; RATE-VARIABILITY;

D O I：

10.1152/physiol.00041.2018

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Lower resting heart rate and high autonomic vagal activity are strongly associated with superior exercise capacity, maintenance of which is essential for general well-being and healthy aging. Recent evidence obtained in experimental studies using the latest advances in molecular neuroscience, combined with human exercise physiology, physiological modeling, and genomic data suggest that the strength of cardiac vagal activity causally determines our ability to exercise.

引用

页码：71 / 80

页数：10

共 90 条

[1] Autonomic regulation of systemic inflammation in humans: A multi-center, blinded observational cohort study [J].

Ackland, Gareth L. ;

Minto, Gary ;

Clark, Martin ;

Whittle, John ;

Stephens, Robert C. M. ;

Owen, Thomas ;

Prabhu, Pradeep ;

del Arroyo, Ana Gutierrez .

BRAIN BEHAVIOR AND IMMUNITY, 2018, 67 :47-53

[2] Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness [J].

Ackland, Gareth L. ;

Whittle, John ;

Toner, Andrew ;

Machhada, Asif ;

Del Arroyo, Ana Gutierrez ;

Sciuso, Alberto ;

Jenkins, Nicholas ;

Dyson, Alex ;

Struthers, Richard ;

Sneyd, J. Robert ;

Minto, Gary ;

Singer, Mervyn ;

Shah, Ajay M. ;

Gourine, Alexander V. .

CRITICAL CARE MEDICINE, 2016, 44 (08) :E614-E624

[3] Effects of right and left vagal stimulation on left ventricular acetylcholine levels in the cat [J].

Akiyama, T ;

Yamazaki, T .

ACTA PHYSIOLOGICA SCANDINAVICA, 2001, 172 (01) :11-16

[4] POWER SPECTRUM ANALYSIS OF HEART-RATE FLUCTUATION - A QUANTITATIVE PROBE OF BEAT-TO-BEAT CARDIOVASCULAR CONTROL [J].

AKSELROD, S ;

GORDON, D ;

UBEL, FA ;

SHANNON, DC ;

BARGER, AC ;

COHEN, RJ .

SCIENCE, 1981, 213 (4504) :220-222

[5]

AlAni M, 1996, EUR J APPL PHYSIOL O, V74, P397

[6] Modulation of Cardiac Ventricular Excitability by GLP-1 (Glucagon-Like Peptide-1) [J].

Ang, Richard ;

Mastitskaya, Svetlana ;

Hosford, Patrick S. ;

Basalay, Marina ;

Specterman, Mark ;

Aziz, Qadeer ;

Li, Yiwen ;

Orini, Michele ;

Taggart, Peter ;

Lambiase, Pier D. ;

Gourine, Andrey ;

Tinker, Andrew ;

Gourine, Alexander V. .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2018, 11 (10) :e006740

[7]

[Anonymous], 1993, HUMAN CARDIOVASCULAR, DOI DOI 10.1249/00005768-199312000-00021

[8] Potential clinical relevance of the 'little brain' on the mammalian heart [J].

Armour, J. A. .

EXPERIMENTAL PHYSIOLOGY, 2008, 93 (02) :165-176

[9] Recent advances in optogenetics and pharmacogenetics [J].

Aston-Jones, Gary ;

Deisseroth, Karl .

BRAIN RESEARCH, 2013, 1511 :1-5

[10] Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning [J].

Basalay, Marina V. ;

Mastitskaya, Svetlana ;

Mrochek, Aleksander ;

Ackland, Gareth L. ;

del Arroyo, Ana Gutierrez ;

Sanchez, Jenifer ;

Sjoquist, Per-Ove ;

Pernow, John ;

Gourine, Alexander V. ;

Gourine, Andrey .

CARDIOVASCULAR RESEARCH, 2016, 112 (03) :669-676

← 1 2 3 4 5 6 7 8 9 →