A phase 1 open-label fixed-sequence two-period crossover study of the effect of multiple doses of tamoxifen on palbociclib (PD-0332991) pharmacokinetics in healthy male volunteers

被引:0
|
作者
Hoffman, Justin T. [1 ]
O'Gorman, Melissa [2 ]
Loi, Cho-Ming [1 ]
Plotka, Anna [3 ]
Boutros, Tanya [1 ]
Kirkovsky, Leonid [1 ]
Stampino, Corrado Gallo [4 ]
Wang, Diane [1 ]
机构
[1] Pfizer, San Diego, CA USA
[2] Pfizer, Groton, CT USA
[3] Pfizer, Collegeville, PA USA
[4] Pfizer, Milan, Italy
关键词
D O I
10.1158/1538-7445.AM2014-LB-229
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
LB-229
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Effects of CYP3A4 inhibition/induction, and OATP inhibition on the pharmacokinetics of atogepant in healthy adults: Two phase 1, open-label, fixed-sequence, single-center, crossover trials
    Boinpally, R.
    Chen, W.
    McGeeney, D.
    Trugman, J. M.
    HEADACHE, 2022, 62 : 107 - 107
  • [42] Bioequivalence of Generic and Branded Subcutaneous Enoxaparin: A Single-Dose, Randomized-Sequence, Open-Label, Two-Period Crossover Study in Healthy Chinese Male Subjects
    Feng, Limin
    Shen-Tu, Jianzhong
    Liu, Jian
    Chen, Junchun
    Wu, Lihua
    Huang, Mingzhu
    CLINICAL THERAPEUTICS, 2009, 31 (07) : 1559 - 1567
  • [43] Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study
    Jia, Caiyun
    Zhao, Na
    Song, Haojing
    Hu, Yiting
    Xu, Yufang
    Guo, Caihui
    Bai, Wanjun
    Dong, Zhanjun
    DRUGS IN R&D, 2024, 24 (04) : 531 - 538
  • [44] A randomized, open-label, two-period crossover study to evaluate the bioequivalence and food effect between two formulations of regorafenib in healthy adult participants
    Li, Yan
    Qi, Lu
    Yang, Caixia
    Zhao, Na
    Wang, Xinghe
    FRONTIERS IN PHARMACOLOGY, 2025, 16
  • [45] Bioavailability of two single-dose oral formulations of omeprazole 20 mg:: An open-label, randomized sequence, two-period crossover comparison in healthy Mexican adult volunteers
    Poo, Jorge Luis
    Galan, Juan Francisco
    Rosete, Alejandra
    de Lago, Alberto
    Oliva, Ivan
    Gonzalez-de la Parra, Mario
    Jimenez, Patricia
    Burke-Fraga, Victoria
    Namur, Salvador
    CLINICAL THERAPEUTICS, 2008, 30 (04) : 693 - 699
  • [46] Relative Bioavailability and Tolerability of Two Formulations of Bicalutamide 50-mg Tablets: A Randomized-Sequence, Open-Label, Two-Period Crossover Study in Healthy Korean Male Subjects
    Lee, SeungHwan
    Yoon, Seo Hyun
    Cho, Joo-Youn
    Shin, Sang-Goo
    Jang, In-Jin
    Yu, Kyung-Sang
    CLINICAL THERAPEUTICS, 2010, 32 (14) : 2496 - 2501
  • [47] Bioequivalence and Pharmacokinetic Comparison of a Single 200-mg Dose of Meclofenoxate Hydrochloride Capsule and Tablet Formulations in Healthy Chinese Adult Male Volunteers: A Randomized Sequence, Open-Label, Two-Period Crossover Study
    Zou, Jian-Jun
    Ji, Hong-Jian
    Wu, Ding-Wei
    Yao, Jing
    Hu, Qin
    Xiao, Da-Wei
    Wang, Guang-Ji
    CLINICAL THERAPEUTICS, 2008, 30 (09) : 1651 - 1657
  • [48] The Effects of Ketoconazole and Rifampicin on the Pharmacokinetics of Mirodenafil in Healthy Korean Male Volunteers: An Open-Label, One-Sequence, Three-Period, Three-Treatment Crossover Study
    Shin, Kwang-Hee
    Kim, Bo-Hyung
    Kim, Tae-Eun
    Kim, Jae Woo
    Yi, SoJeong
    Yoon, Seo-Hyun
    Cho, Joo-Youn
    Shin, Sang-Goo
    Jang, In-Jin
    Yu, Kyung-Sang
    CLINICAL THERAPEUTICS, 2009, 31 (12) : 3009 - 3020
  • [49] Pharmacokinetic and Bioequivalence Comparison Between Orally Disintegrating and Conventional Tablet Formulations of Flurbiprofen: A Single-Dose, Randomized-Sequence, Open-Label, Two-Period Crossover Study in Healthy Chinese Male Volunteers
    Liu, Yan-Mei
    Liu, Gang-Yi
    Liu, Yun
    Li, Shui-Jun
    Jia, Jing-Ying
    Zhang, Meng-Qi
    Lu, Chuan
    Zhang, Yong-Mei
    Li, Xue-Ning
    Yu, Chen
    CLINICAL THERAPEUTICS, 2009, 31 (08) : 1787 - 1795
  • [50] Evaluating the pharmacokinetics and safety of blonanserin tablets and Lonasen®: a randomized, open-label, two-period, two-sequence, self-crossover phase I clinical trial
    Qiu, Bo
    Song, Haojing
    Sun, Xue
    Ding, Congyang
    Du, Runxuan
    Bai, Wanjun
    Dong, Zhanjun
    FRONTIERS IN PHARMACOLOGY, 2025, 15