A phase 1 open-label fixed-sequence two-period crossover study of the effect of multiple doses of tamoxifen on palbociclib (PD-0332991) pharmacokinetics in healthy male volunteers

被引：0
|
作者：
Hoffman, Justin T. [1 ]
O'Gorman, Melissa [2 ]
Loi, Cho-Ming [1 ]
Plotka, Anna [3 ]
Boutros, Tanya [1 ]
Kirkovsky, Leonid [1 ]
Stampino, Corrado Gallo [4 ]
Wang, Diane [1 ]
机构：
[1] Pfizer, San Diego, CA USA
[2] Pfizer, Groton, CT USA
[3] Pfizer, Collegeville, PA USA
[4] Pfizer, Milan, Italy
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-LB-229
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-229
引用
收藏
页数：2
相关论文
共 50 条
  • [1] A phase I open-label, fixed-sequence, two-period crossover study of the effect of multiple doses of Itraconazole on Palbociclib (PD-0332991) pharmacokinetics in healthy volunteers
    Hoffman, Justin T.
    Loi, Cho-Ming
    O'Gorman, Melissa
    Plotka, Anna
    Kosa, Maha
    Jakubowska, Anna
    Wang, Diane D.
    CANCER RESEARCH, 2016, 76
  • [2] A phase I open-label fixed sequence two-period crossover study of the effect of multiple doses of modafinil on palbociclib (PD-0332991) pharmacokinetics in healthy volunteers
    Hoffman, Justin T.
    Loi, Cho-Ming
    Plotka, Anna
    O'Gorman, Melissa
    Shi, Haihong
    Mori, Ave
    Wang, Diane D.
    CANCER RESEARCH, 2016, 76
  • [3] A phase 1 randomized, openlabel, fixed-sequence, 2-period study of the effect of multiple doses of rifampin on palbociclib (PD-0332991) pharmacokinetics in healthy volunteers
    Hoffman, Justin T.
    Plotka, Anna
    O'Gorman, Melissa
    Chan, Andrew
    Kosa, Maha
    Loi, Cho-Ming
    Gallo-Stampino, Corrado
    Wang, Diane D.
    CANCER RESEARCH, 2015, 75
  • [4] A phase 1 randomized, open-label, 2-sequence, 2-period crossover study of the effect of multiple doses of palbociclib (PD-0332991) on midazolam pharmacokinetics in healthy women of non-childbearing potential
    Hoffman, Justin T.
    Plotka, Anna
    O'Gorman, Melissa
    Loi, Cho-Ming
    Kirkovsky, Leonid
    Gallo-Stampino, Corrado
    Wang, Diane
    CANCER RESEARCH, 2014, 74 (19)
  • [5] The Effects of Boceprevir and Telaprevir on the Pharmacokinetics of Maraviroc: An Open-Label, Fixed-Sequence Study in Healthy Volunteers
    Vourvahis, Manoli
    Plotka, Anna
    Kantaridis, Constantino
    Fang, Annie
    Heera, Jayvant
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2014, 65 (05) : 564 - 570
  • [6] Effect of Multiple Oral Doses of Linagliptin on the Steady-State Pharmacokinetics of a Combination Oral Contraceptive in Healthy Female Adults An Open-Label, Two-Period, Fixed-Sequence, Multiple-Dose Study
    Friedrich, Christian
    Port, Andreas
    Ring, Arne
    Graefe-Mody, Ulrike
    Giessmann, Thomas
    Iovino, Mario
    Woerle, Hans-Juergen
    CLINICAL DRUG INVESTIGATION, 2011, 31 (09) : 643 - 653
  • [7] Effect of Multiple Oral Doses of Linagliptin on the Steady-State Pharmacokinetics of a Combination Oral Contraceptive in Healthy Female AdultsAn Open-Label, Two-Period, Fixed-Sequence, Multiple-Dose Study
    Christian Friedrich
    Andreas Port
    Arne Ring
    Ulrike Graefe-Mody
    Thomas Giessmann
    Mario Iovino
    Hans-Juergen Woerle
    Clinical Drug Investigation, 2011, 31 : 643 - 653
  • [8] Effect of Steady-State Faldaprevir on Pharmacokinetics of Atorvastatin or Rosuvastatin in Healthy Volunteers: A Prospective Open-Label, Fixed-Sequence Crossover Study
    Huang, Fenglei
    Marzin, Kristell
    Koenen, Ruediger
    Kammerer, Klaus Peter
    Strelkowa, Natalja
    Elgadi, Mabrouk
    Quinson, Anne-Marie
    Haertter, Sebastian
    JOURNAL OF CLINICAL PHARMACOLOGY, 2017, 57 (10): : 1305 - 1314
  • [9] An Open-Label, Randomized, Single-Center, Two-Period, Phase I, Crossover Study of the Effect of Zibotentan (ZD4054) on the Pharmacokinetics of Midazolam in Healthy Male Volunteers
    Tomkinson, Helen K.
    Kemp, John V.
    Wollseifen, Thomas
    Morris, Thomas
    Oliver, Stuart D.
    CLINICAL THERAPEUTICS, 2010, 32 (07) : 1372 - 1386
  • [10] Bioequivalence Evaluation of Single Doses of Two Tramadol Formulations: A Randomized, Open-Label, Two-Period Crossover Study in Healthy Brazilian Volunteers
    Silva, Marina de Freitas
    Schramm, Simone Grigoleto
    Kano, Eunice Kazue
    Mori Koono, Eunice Emiko
    Porta, Valentina
    dos Reis Serra, Cristina Helena
    CLINICAL THERAPEUTICS, 2010, 32 (04) : 758 - 765
12345