Recent progress on donor and donor-donor carbenes

被引：310

作者：

Zhu, Dong ^{[1
]}

Chen, Lianfen ^{[1
]}

Fan, Hanlin ^{[1
]}

Yao, Qinglin ^{[1
]}

Zhu, Shifa ^{[1
,2
]}

机构：

[1] South China Univ Technol, Key Lab Funct Mol Engn Guangdong Prov, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China

[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

CHEMICAL SOCIETY REVIEWS | 2020年 / 49卷 / 03期

关键词：

C-H INSERTION; OLEFIN-METATHESIS CATALYSTS; RETRO-BUCHNER REACTION; ENE-YNE-KETONES; RUTHENIUM ALLENYLIDENE COMPLEXES; ELECTRON-DEFICIENT ALKENES; N-TOSYLHYDRAZONES BEARING; CROSS-COUPLING REACTIONS; IN-SITU GENERATION; ONE-POT REACTION;

D O I：

10.1039/c9cs00542k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Donor and donor-donor carbenes are two important kinds of carbenes, which have experienced tremendous growth in the past two decades. This review provides a comprehensive overview of the recent development of donor and donor-donor carbene chemistry. The development of this chemistry offers efficient protocols to construct a wide variety of C-C and C-X bonds in organic synthesis. This review is organized based on the different types of carbene precursors, including diazo compounds, hydrazones, enynones, cycloheptatrienes and cyclopropenes. The typical transformations, the reaction mechanisms, as well as their subsequent applications in the synthesis of complex natural products and bioactive molecules are discussed. Due to the rapidly increasing interest in this area, we believe that this review will provide a timely and comprehensive discussion of recent progress in donor and donor-donor carbene chemistry.

引用

页码：908 / 950

页数：43

共 287 条

[41] Ruthenium porphyrin catalyzed intramolecular carbenoid C-H insertion. Stereloselective synthesis of cis-disubstituted oxygen and nitrogen heterocycles [J].