Ultrahigh resolution optical coherence tomography for enhanced visualization of retinal pathology

被引:0
|
作者
Ko, T [1 ]
Drexler, W [1 ]
Paunescu, LA [1 ]
Hartl, I [1 ]
Ghanta, R [1 ]
Schuman, J [1 ]
Fujimoto, J [1 ]
机构
[1] MIT, Dept Elect Engn & Comp Sci, Elect Res Lab, Cambridge, MA 02139 USA
关键词
D O I
10.1117/12.479032
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An ultrahigh resolution ophthalmic optical coherence tomography (OCT) system has been developed. Using a: femtosecond Ti: sapphire laser light source, Which generates bandwidths of similar to150 nm at 800 nm, real-time, cross-sectional imaging of the retina with similar to3 mum axial resolution is possible. Ultrahigh resolution OCT images of retinal morphology were obtained in normal subjects and patients with retinal disease. Intraretinal architectural morphology associated with macular diseases such as macular edema, epiretinal membranes, and macular holes can be visualized with unprecedented resolution. Ultrahigh resolution ophthalmic OCT promises to improve the early diagnosis of retinal diseases as well as enable monitoring of disease progression and the efficacy of therapeutic intervention.
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页码:55 / 58
页数:4
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