Lactic Acid-Catalyzed Transamidation Reactions of Carboxamides with Amines

被引:1
作者
Liu, Juyan [1 ]
Zhao, Congying [1 ]
机构
[1] Tianjin Normal Univ, Coll Chem, Tianjin Key Lab Struct & Performance Funct Mol, Tianjin 300387, Peoples R China
关键词
lactic acid; carboxamide; urea; transamidation; HIGHLY EFFICIENT CATALYST; AMIDE BOND FORMATION; L-PROLINE; AMIDATION; DISCOVERY; CHLORIDE; UREAS;
D O I
10.6023/cjoc202010010
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An environmentally benign protocol for the transamidation of carboxamides with amines using lactic acid as a green catalyst has been developed. The method has been successfully applied to the synthesis of a wide range of aromatic and aliphatic amides and ureas. The reaction has the advantages of the ready accessibility of the catalyst, solvent-free condition, efficient transformation and green processing.
引用
收藏
页码:2310 / 2318
页数:9
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