Dual-winding permanent magnet motor (DWPMM) drive system has high power density, high efficiency, take up a small amount of space and lower torque fluctuation, besides it has powerful ability of magnetic, thermal, and physical isolation. In this paper, a strong fault-tolerant control strategy for open-circuit fault of power switch based on high reliable DWPMM drive system is proposed. The fault-tolerance ability of the DWPMM drive system under open-circuit fault of power switch has been confirmed by simulation. The DWPMM drive system can be operated normally when the power switch occurs an open-circuit. The simulation results confirm the correctness of the proposed strong robustness fault-tolerant control strategy.