Genetics of Equine Neurologic Disease

被引:5
作者
Edwards, Lisa [1 ]
Finno, Carrie J. [1 ]
机构
[1] Univ Calif Davis, Sch Vet Med, Dept Vet Populat Hlth & Reprod, Room 4206,Vet Med 3A,One Shields Ave, Davis, CA 95616 USA
关键词
Ataxia; Horse; Inherited; Paresis; Seizure; WHITE FOAL SYNDROME; MOTOR-NEURON DISEASE; VITAMIN-E-DEFICIENCY; EGYPTIAN ARABIAN FOALS; NEUROAXONAL DYSTROPHY; OCCIPITOATLANTOAXIAL MALFORMATION; DEGENERATIVE MYELOENCEPHALOPATHY; CONGENITAL HYDROCEPHALUS; CEREBELLAR ABIOTROPHY; MISSENSE MUTATION;
D O I
10.1016/j.cveq.2020.03.006
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Neurologic disease in horses can be particularly challenging to diagnose and treat. These diseases can result in economic losses, emotional distress to owners, and injury to the horse or handlers. To date, there are five neurologic diseases caused by known genetic mutations and several more are suspected to be heritable: lethal white foal syndrome (LWFS), lavender foal syndrome (LFS), cerebellar abiotrophy (CA), occipitoatlantoaxial malformation (OAAM), and Friesian hydrocephalus. Genetic testing allows owners, breeders, and veterinarians to make informed decisions when selecting dams and sires for breeding or deciding the treatment or prognosis of a neurologic animal.
引用
收藏
页码:255 / +
页数:19
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