Surveillance of Transmitted HIV-1 Drug Resistance in Gauteng and KwaZulu-Natal Provinces, South Africa, 2005-2009

被引：32
作者：
Hunt, G. M. [1 ]
Ledwaba, J.
Basson, A. E.
Moyes, J.
Cohen, C.
Singh, B.
Bertagnolio, S. [2 ]
Jordan, M. R. [2 ,3 ]
Puren, A.
Morris, L.
机构：
[1] Natl Inst Communicable Dis, AIDS Virus Res Unit, ZA-2131 Johannesburg, South Africa
[2] World Hlth Org, Geneva, Switzerland
[3] Tufts Univ, Sch Med, Boston, MA 02111 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2012年 / 54卷
基金：
比尔及梅琳达.盖茨基金会;
关键词：
CAPTURE ENZYME-IMMUNOASSAY; ANTIRETROVIRAL THERAPY; INDIVIDUALS; PREVALENCE; MUTATIONS; COUNTRIES; FAILURE;
D O I：
10.1093/cid/cir1017
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (< 5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.
引用
收藏
页码：S334 / S338
页数：5
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