Objective: to investigate, in the literature, the prevalent nursing diagnoses in assistance to potential brain-dead organ donors. Method: this is an integrative review, conducted by the guiding question: What is the scientific evidence about the prevalent nursing diagnoses in assisting brain-dead organ donor patients? The search was performed in LILACS, BDENF, CINAHL, MEDLINE and Cochrane Library databases. Results: the final sample consisted of seven articles that address the prevalent nursing diagnoses in care delivery to brain-dead organ donor patients. Data were organized into two thematic categories: Main diagnoses, pathophysiological changes and defining characteristics, and Knowledge of nursing professionals in the face of brain death for early diagnosis. Conclusion: assistance to potential donors is essential for the donation to be effected, therefore, nursing diagnoses are the basis for these professionals to plan all assistance.