Blepharoptosis surgery in patients with myasthenia gravis
被引:20
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作者:
Litwin, Andre S.
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Queen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, EnglandQueen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
Litwin, Andre S.
[1
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Patel, Bhupendra
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机构:
Univ Utah, Moran Eye Ctr, Div Facial & Orbital Cosmet & Reconstruct Surg, Salt Lake City, UT USAQueen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
Patel, Bhupendra
[2
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McNab, Alan A.
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机构:
Royal Victorian Eye & Ear Hosp, Orbital Plast & Lacrimal Clin, Melbourne, Vic 3002, AustraliaQueen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
McNab, Alan A.
[3
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McCann, John D.
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机构:
Ctr Facial Appearances, Salt Lake City, UT USAQueen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
McCann, John D.
[4
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Leatherbarrow, Brian
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Manchester Royal Eye Hosp, Manchester M13 9WH, Lancs, EnglandQueen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
Leatherbarrow, Brian
[5
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机构:
Malhotra, Raman
[1
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机构:
[1] Queen Victoria Hosp NHS Trust, Corneoplast Unit, E Grinstead RH19 3DZ, W Sussex, England
[2] Univ Utah, Moran Eye Ctr, Div Facial & Orbital Cosmet & Reconstruct Surg, Salt Lake City, UT USA
[3] Royal Victorian Eye & Ear Hosp, Orbital Plast & Lacrimal Clin, Melbourne, Vic 3002, Australia
[4] Ctr Facial Appearances, Salt Lake City, UT USA
[5] Manchester Royal Eye Hosp, Manchester M13 9WH, Lancs, England
Background/aims To review our approach of cautious surgical correction of blepharoptosis in patients with myasthenia gravis (MG) to minimise risk of exposure complications. Methods Retrospective case note review of 30 patients with symptomatic eyelid concerns despite appropriate medical treatment, who underwent eyelid surgery. The mean age at diagnosis was 47 years. 13/30 patients had systemic MG, 14/30 ocular MG and 3/30 congenital MG. The main outcome measures were improvement in eyelid height and/or position, duration of a successful postoperative result, need for further surgical intervention, and intraoperative or postoperative complications. Results 38 blepharoptosis procedures were performed on 23 patients. Mean age at time of surgery was 62 years, with an average follow-up of 29 months. 10 patients (16 eyelids) underwent anterior approach levator advancement, 4 patients (5 eyelids) posterior approach surgery and 8 patients (15 eyelids) brow suspension. One patient (2 eyelids) had tarsal switch surgery. An average improvement in eyelid height of 1.9 mm was achieved. Postoperative symptoms or signs of exposure keratopathy occurred in 17% of patients. This necessitated lid lowering in one eyelid of one patient. During follow-up, 37% of eyelids required further surgical intervention to improve the upper eyelid height, after an average of 19 months (range 0.5-49 months). Conclusions Over a third of patients in our series required repeat surgery, which would be expected when the initial aim was to under-correct this group. In contrast to previous commentaries, the amount of eyelid excursion was not the main factor used to guide the surgical approach.
机构:
Univ Pisa, Div Med Genet, Dept Translat Res & New Technol Med & Surg, Pisa, ItalyUniv Pisa, Div Med Genet, Dept Translat Res & New Technol Med & Surg, Pisa, Italy
Lopomo, Angela
Berrih-Aknin, Sonia
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UPMC Univ Paris 06, Sorbonne Univ, Paris, France
INSERM, U974, Paris, France
Inst Myol, AIM, Paris, FranceUniv Pisa, Div Med Genet, Dept Translat Res & New Technol Med & Surg, Pisa, Italy
机构:
Virginia Commonwealth Univ, Dept Neurol, Richmond, VA 23298 USA
Virginia Commonwealth Univ, Dept Ophthalmol, Richmond, VA 23298 USAVirginia Commonwealth Univ, Dept Neurol, Richmond, VA 23298 USA
Haines, Scott R.
Thurtell, Matthew J.
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机构:Virginia Commonwealth Univ, Dept Neurol, Richmond, VA 23298 USA
机构:
George Washington Univ, Dept Neurol, Washington, DC USAGeorge Washington Univ, Dept Neurol, Washington, DC USA
Sengupta, Manjistha
Cheema, Amrita
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机构:
Georgetown Univ, Med Ctr, Lombardi Comprehens Canc Ctr, Dept Oncol, Washington, DC 20007 USAGeorge Washington Univ, Dept Neurol, Washington, DC USA
Cheema, Amrita
Kaminski, Henry J.
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George Washington Univ, Dept Neurol, Washington, DC USAGeorge Washington Univ, Dept Neurol, Washington, DC USA
Kaminski, Henry J.
Kusner, Linda L.
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机构:
George Washington Univ, Dept Physiol & Pharmacol, Washington, DC 20052 USAGeorge Washington Univ, Dept Neurol, Washington, DC USA