Effects of electromagnetic radiation produced by 3G mobile phones on rat brains: Magnetic resonance spectroscopy, biochemical, and histopathological evaluation

被引：19

作者：

Dogan, M. ^{[1
]}

Turtay, M. G. ^{[2
]}

Oguzturk, H. ^{[2
]}

Samdanci, E. ^{[3
]}

Turkoz, Y. ^{[4
]}

Tasdemir, S. ^{[5
]}

Alkan, A.

Bakir, S.

机构：

[1] Inonu Univ, Sch Med, Turgut Ozal Med Ctr, Dept Radiol, TR-44315 Malatya, Turkey

[2] Inonu Univ, Sch Med, Dept Emergency Med, TR-44315 Malatya, Turkey

[3] Inonu Univ, Sch Med, Dept Pathol, TR-44315 Malatya, Turkey

[4] Inonu Univ, Sch Med, Dept Biochem, TR-44315 Malatya, Turkey

[5] Inonu Univ, Sch Med, Dept Pharmacol, TR-44315 Malatya, Turkey

来源：

HUMAN & EXPERIMENTAL TOXICOLOGY | 2012年 / 31卷 / 06期

关键词：

third-generation mobile phone; electromagnetic radiation; magnetic resonance spectroscopy; oxidative stress; PROTON MR SPECTROSCOPY; OXIDATIVE STRESS; CELLULAR PHONE; 1800; MHZ; EXPOSURE; TUMORS; TELEPHONES; FIELDS; CELLS;

D O I：

10.1177/0960327111412092

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Objective: The effects of electromagnetic radiation (EMR) produced by a third-generation (3G) mobile phone (MP) on rat brain tissues were investigated in terms of magnetic resonance spectroscopy (MRS), biochemistry, and histopathological evaluations. Methods: The rats were randomly assigned to two groups: Group I is composed of 3G-EMR-exposed rats (n = 9) and Group 2 is the control group (n = 9). The first group was subjected to EMR for 20 days. The control group was not exposed to EMR. Choline (Cho), creatinin (Cr), and N-acetylaspartate (NAA) levels were evaluated by MRS. Catalase (CAT) and glutathione peroxidase (GSH-Px) enzyme activities were measured by spectrophotometric method. Histopathological analyses were carried out to evaluate apoptosis in the brain tissues of both groups. Results: In MRS, NAA/Cr, Cho/Cr, and NAA/Cho ratios were not significantly different between Groups I and 2. Neither the oxidative stress parameters, CAT and GSH-Px, nor the number of apoptotic cells were significantly different between Groups I and 2. Conclusions: Usage of short-term 3G MP does not seem to have a harmful effect on rat brain tissue.

引用

页码：557 / 564

页数：8

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