Synthetic cells-self-assembling polymer membranes and bioadhesive colloids

被引：46
作者：
Hammer, DA [1 ]
Discher, DE [1 ]
机构：
[1] Univ Penn, Sch Engn & Appl Sci, Philadelphia, PA 19104 USA
来源：
ANNUAL REVIEW OF MATERIALS RESEARCH | 2001年 / 31卷 / 31期
关键词：
polymer vesicles; biocolloids; artificial cells;
D O I：
10.1146/annurev.matsci.31.1.387
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We summarize developments in the construction of synthetic cells made from polymers, with a particular focus on mimicking the structure and behavior of blood cells. Two basic themes emerge-the use of block copolymers to make polmer vesicles and the functionalization of colloidal or polymeric microspheres with cell-like adhesive properties. Both platforms provide a means for building the complex hierarchy that is characteristic of biological cells, while also incorporating novel and perhaps superior properties of material strength, specific targeting, and controlled release.
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页码：387 / 404
页数：22
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