Treatment of adult Graves' disease

被引:22
|
作者
Corvilain, Bernard [1 ]
Hamy, Antoine [2 ]
Brunaud, Laurent [3 ]
Borson-Chazot, Francoise [4 ]
Orgiazzi, Jacques [5 ]
Hachmi, Leila Bensalem [6 ]
Semrouni, Mourad [7 ]
Rodien, Patrice [8 ]
Lussey-Lepoutre, Charlotte [9 ]
机构
[1] Univ Libre Bruxelles, Erasme Univ Hosp, Dept Endocrinol, Brussels, Belgium
[2] CHU Angers, Serv Chirurg Viscerale & Endocrine, F-49000 Angers, France
[3] Univ Lorraine, Unite Multidisciplinaire Chirurg Obesite, Unite Chirurg Endocrinienne Thyroidienne & Metab, Serv Chirurg,CHU Nancy,Hop Brabois Adultes, 11 Allee Morvan, F-54511 Vandoeuvre Les Nancy, France
[4] Univ Claude Bernard Lyon 1, Federat Endocrinol, HESPER EA 7425, Hosp Civils Lyon, F-69008 Lyon, France
[5] Univ Claude Bernard Lyon 1, CERMEP Imagerie Vivant, Lyon, France
[6] Inst Natl Nutr Tunis, Serv Endocrinol, Fac Med Tunis, Tunis, Tunisia
[7] CHU Beni Messous, Dept Med, Algiers, Algeria
[8] CHU Angers, Serv EDN, Ctr Reference Malad Rares Thyroide & Recepteurs H, F-49000 Angers, France
[9] Sorbonne Univ, Grp Hosp Pitie Salpetriere, Serv Med Nucl, Inserm U970, F-75013 Paris, France
关键词
Graves' disease; Surgery; Antithyroid drugs; Radioiodine; Orbitopathy; Pregnancy; Thyroid dermopathy; ANTITHYROID DRUG-THERAPY; RADIOACTIVE IODINE THERAPY; QUALITY-OF-LIFE; THYROID-HORMONE LEVELS; MONOCLONAL-ANTIBODY RITUXIMAB; HUMAN BREAST-MILK; RADIOIODINE TREATMENT; HYPERTHYROID PATIENTS; POTASSIUM-IODIDE; CANCER-MORTALITY;
D O I
10.1016/j.ando.2018.08.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Treatment strategy in Graves' disease firstly requires recovery of euthyroid status by antithyroid therapy. Treatment modalities, precautions, advantages and side-effects are to be discussed with the patient. No particular treatment modality has demonstrated superiority. Pregnancy or pregnancy project affects choice of treatment and monitoring. Graves' orbitopathy is liable to be aggravated by iodine-131 treatment and requires pre-treatment assessment. Iodine-131 treatment aims at achieving hypothyroidism. Thyroid surgery for Graves' disease should preferably be performed by an expert team. In case of recurrence of hyperthyroidism, the various treatment options should be discussed with the patient. Empiric treatment of thyroid dermopathy uses local corticosteroids in occlusive dressing. (C) 2018 Published by Elsevier Masson SAS.
引用
收藏
页码:618 / 635
页数:18
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