Easypod™:: a new electronic injection device for growth hormone

被引:31
作者
Dahlgren, Jovanna [1 ]
机构
[1] Queen Silvia Childrens Hosp, Dept Paediat, GP GRC, S-41685 Gothenburg, Sweden
关键词
easypod (TM); electronic injection device; growth hormone;
D O I
10.1586/17434440.5.3.297
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The easypod (TM) is the first automated electronic injection device for growth hormone delivery. To save user's time and reduce administration error, the dose is preset by a physician or nurse; in addition, to allow patient adherence to be monitored, the time, date and dose (mg) of each injection is recorded. Details of the last injection and number of doses remaining in the cartridge are also displayed in order to help patients manage the injection schedule. Drug use can be optimized by splitting the dose over two cartridges, with an automatic compensation facility to avoid under-dosing. Patients can customize the depth, speed and duration of the injection. In a user trial, easypod was very well accepted. This review places easypod in the context of current and future growth hormone devices.
引用
收藏
页码:297 / 304
页数:8
相关论文
共 32 条
[1]   Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults -: a KIMS database analysis [J].
Abs, Roger ;
Feldt-Rasmussen, Ulla ;
Mattsson, Anders F. ;
Monson, John P. ;
Bengtsson, Bengt-Ake ;
Goth, Miklos I. ;
Wilton, Patrick ;
Koltowska-Haggstrom, Maria .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2006, 155 (01) :79-90
[2]  
AHMED SF, 2007, ARCH DIS CHILD, V93, P95
[3]  
Allen DB, 2004, J PEDIATR ENDOCR MET, V17, P1297
[4]   Continued growth hormone (GH) treatment after final height is necessary to complete somatic development in childhood-onset GH-deficient patients [J].
Attanasio, AF ;
Shavrikova, E ;
Blum, WF ;
Cromer, M ;
Child, CJ ;
Paskova, M ;
Lebl, J ;
Chipman, JJ ;
Shalet, SM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (10) :4857-4862
[5]   Growth hormone is effective in treatment of short stature associated with short stature homeobox-containing gene deficiency: Two-year results of a randomized, controlled, multicenter trial [J].
Blum, Werner F. ;
Crowe, Brenda J. ;
Quigley, Charmian A. ;
Jung, Heike ;
Cao, Dachuang ;
Ross, Judith L. ;
Braun, LeeAnn ;
Rappold, Gudrun .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (01) :219-228
[6]   Clinical practice guideline - Care of girls and women with Turner syndrome: A guideline of the Turner Syndrome Study Group [J].
Bondy, Carolyn A. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (01) :10-25
[7]   Management of the child born small for gestational age through to adulthood: A consensus statement of the international societies of pediatric endocrinology and the Growth Hormone Research Society [J].
Clayton, P. E. ;
Cianfarani, S. ;
Czernichow, P. ;
Johannsson, G. ;
Rapaport, R. ;
Rogol, A. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (03) :804-810
[8]   Consensus statement on the management of the GH-treated adolescent in the transition to adult care [J].
Clayton, PE ;
Cuneo, RC ;
Juul, A ;
Monson, JP ;
Shalet, SM ;
Tauber, M .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2005, 152 (02) :165-170
[9]   Patient acceptance of a novel electronic auto-injector device to administer recombinant human growth hormone: results from an open-label, user survey of everyday use [J].
Dahlgren, J. ;
Veimo, D. ;
Johansson, L. ;
Bech, I. .
CURRENT MEDICAL RESEARCH AND OPINION, 2007, 23 (07) :1649-1655
[10]   Final height in short children born small for gestational age treated with growth hormone [J].
Dahlgren, J ;
Wikland, KA .
PEDIATRIC RESEARCH, 2005, 57 (02) :216-222