Acinetobacter calcoaceticus-Acinetobacter baumannii complex species in clinical specimens in Singapore

被引：23

作者：

Koh, T. H. ^{[1
,2
]}

Tan, T. T. ^{[3
]}

Khoo, C. T. ^{[3
]}

Ng, S. Y. ^{[4
]}

Tan, T. Y. ^{[4
]}

Hsu, L-Y ^{[2
]}

Ooi, E. E. ^{[5
]}

van der Reijden, T. J. K. ^{[6
]}

Dijkshoorn, L. ^{[6
]}

机构：

[1] Singapore Gen Hosp, Dept Pathol, Singapore 169608, Singapore

[2] Natl Univ Singapore Hosp, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore

[3] Singapore Gen Hosp, Dept Infect Dis, Singapore 169608, Singapore

[4] Changi Gen Hosp, Dept Lab Med, Singapore, Singapore

[5] Duke NUS Grad Med Sch, Singapore, Singapore

[6] Leiden Univ, Med Ctr, Dept Infect Dis, Leiden, Netherlands

来源：

EPIDEMIOLOGY AND INFECTION | 2012年 / 140卷 / 03期

关键词：

Antibiotic resistance; bacterial infections; bacterial typing; hospital microbiology; molecular epidemiology; BLA(OXA-51-LIKE); IDENTIFICATION; RESISTANCE; EXPRESSION; STRAINS; CLONE; PCR;

D O I：

10.1017/S0950268811001129

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This study was performed to determine the prevalence, distribution of specimen sources, and antimicrobial susceptibility of the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) species complex in Singapore. One hundred and ninety-three non-replicate Acb species complex clinical isolates were collected from six hospitals over a 1-month period in 2006. Of these, 152 (78.7%) were identified as A. baumannii, 18 (9.3%) as 'Acinetobacter pittii' [genomic species (gen. sp.) 3], and 23 (11.9%) as 'Acinetobacter nosocomialis' (gen. sp. 13TU). Carbapenem resistance was highest in A. baumannii (72.4%), followed by A. pittii (38.9%), and A. nosocomialis (34.8%). Most carbapenem-resistant A. baumannii and A. nosocomialis possessed the blaOXA-23-like gene whereas carbapenem-resistant A. pittii possessed the blaOXA-58-like gene. Two imipenem-resistant strains (A. baumannii and A. pittii) had the blaIMP-like gene. Representatives of carbapenem-resistant A. baumannii were related to European clones I and II.

引用

页码：535 / 538

页数：4

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