Cloning and expression of prion protein encoding gene of flounder (Paralichthys olivaceus)

被引：0

作者：

Zhang Zhiwen ^{[1
,2
]}

Sun Xiuqin ^{[1
]}

Zhang Jinxing ^{[1
,2
]}

Zan Jindong ^{[1
,2
]}

机构：

[1] Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Peoples R China

[2] State Ocean Adm China, Inst Oceanog 1, Qingdao 266061, Peoples R China

来源：

CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY | 2008年 / 26卷 / 01期

关键词：

bastard halibut; Paralichthys olivaceus; prion protein; PrP; gene; clone; expression;

D O I：

10.1007/s00343-008-0050-3

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The prion protein (PrP) encoding gene of flounder (Paralichthys olivaceus) was cloned. It was not interrupted by an intron. This gene has two promoters in its 5' upstream, indicating that its transcription may be intensive, and should have an important function. It was expressed in all 14 tissues tested, demonstrating that it is a house-keeping gene. Its expression in digestion and reproduction systems implies that the possible prions of fish may transfer horizontally.

引用

页码：50 / 53

页数：4

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