Biased by design? Clinical trials and patient benefit in oncology

被引：3
|
作者：
Pantziarka, Pan [1 ,2 ]
Verbaanderd, Ciska [1 ,3 ]
Meheus, Lydie [1 ]
机构：
[1] Anticanc Fund, 1853 Strombeek Bever, Brussels, Belgium
[2] George Pantziarka TP53 Trust, London, England
[3] Katholieke Univ Leuven, Clin Pharmacol & Pharmacotherapy, Dept Pharmaceut & Pharmacol Sci, Leuven, Belgium
来源：
FUTURE ONCOLOGY | 2020年 / 16卷 / 03期
关键词：
clinical trial design; drug development; drug registration; patient benefit; risks of bias; SCIENTIFIC ADVICE; CANCER; DRUGS; MAGNITUDE; THERAPIES; SURVIVAL; APPROVAL;
D O I：
10.2217/fon-2019-0763
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：4419 / 4423
页数：5
相关论文
共 50 条
  • [1] Clinical benefit in oncology trials: Is this a patient-centred or tumour-centred end-point?
    Ohorodnyk, Paulo
    Eisenhauer, Elizabeth A.
    Booth, Christopher M.
    EUROPEAN JOURNAL OF CANCER, 2009, 45 (13) : 2249 - 2252
  • [2] Veterinary oncology clinical trials: Design and implementation
    Thamm, Douglas H.
    Vail, David M.
    VETERINARY JOURNAL, 2015, 205 (02) : 226 - 232
  • [3] Endpoints in oncology clinical trials
    Kilickap, Saadettin
    Demirci, Umut
    Karadurmus, Nuri
    Dogan, Mutlu
    Akinci, Bulent
    Sendur, Mehmet Ali Nahit
    JOURNAL OF BUON, 2018, 23 : S1 - S6
  • [4] Increasing patient participation in oncology clinical trials
    Chen, Jie
    Lu, Ying
    Kummar, Shivaani
    CANCER MEDICINE, 2023, 12 (03): : 2219 - 2226
  • [5] Evidence synthesis analysis with prioritized benefit outcomes in oncology clinical trials
    Cui, Ying
    Dong, Gaohong
    Kuan, Pei Fen
    Huang, Bo
    JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2023, 33 (03) : 272 - 288
  • [6] Assessing patient burden and benefit: A decade of cabozantinib clinical trials
    Hughes, Griffin K.
    Sajjadi, Nicholas B.
    Gardner, Brooke
    Ramoin, Joshua K.
    Tuia, Jordan
    Haslam, Alyson
    Prasad, Vinay
    Vassar, Matt
    INTERNATIONAL JOURNAL OF CANCER, 2024, 154 (08) : 1464 - 1473
  • [7] Optimising the design of phase II oncology trials: The importance of randomisation
    Ratain, Mark J.
    Sargent, Daniel J.
    EUROPEAN JOURNAL OF CANCER, 2009, 45 (02) : 275 - 280
  • [8] Overcoming Organizational Challenges of Integrating Patient-Reported Outcomes in Oncology Clinical Trials
    Gnanasakthy, Ari
    DeMuro, Carla
    THERAPEUTIC INNOVATION & REGULATORY SCIENCE, 2015, 49 (06) : 822 - 830
  • [9] Impact of the Economic Status of the Patient's Country of Residence on the Outcome of Oncology Clinical Trials
    Nishiyama, Saki
    Narukawa, Mamoru
    Aly, Abdalla
    ONCOLOGIST, 2022, 27 (03) : E244 - E250
  • [10] What is the expected benefit of patient-centric clinical development in oncology?
    Serra, Alessandra
    Mozgunov, Pavel
    Jaki, Thomas
    Rigat, Fabio
    JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2022, 32 (03) : 414 - 426
12345