WILMA - automated annotation of protein sequences

被引:8
|
作者
Prlic, A
Domingues, FS
Lackner, P
Sippl, MJ
机构
[1] Salzburg Univ, Inst Chem & Biochem, Ctr Appl Mol Engn, A-5020 Salzburg, Austria
[2] Max Planck Inst Informat, D-66123 Saarbrucken, Germany
基金
奥地利科学基金会;
关键词
D O I
10.1093/bioinformatics/btg380
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Large-scale annotation of sets of proteins is a frequently occurring task in association with genome sequencing projects. Here, we present an automated platform for the functional annotation of large sets of protein sequences. Various bioinformatics tools are used to achieve a comprehensive description of protein sequences and to link these results to standard Gene Ontology descriptors for molecular function, biological processes and cellular components. Access to the annotation is provided via a web-interface and database queries. These interfaces allow to formulate proteome wide queries as well as the investigation of details of individual results. WILMA annotations of the proteomes of Homo sapiens, Mus musculus, Arabidopsis thaliana and Caenorhabditis elegans are accessible at http://www.came.sbg.ac.at/wilma/.
引用
收藏
页码:127 / 128
页数:2
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