Ovarian Sertoli-Leydig Cell Tumor with Predominant Heterologous Mucinous Differentiation and Foci of Hepatocytic Differentiation: Case Report and Review of The Literature

被引：0
|
作者：
Liang, Li [1 ,3 ]
Menzin, Andrew [2 ]
Lovecchio, John Louis [2 ]
Navarro, Maria D. [1 ]
机构：
[1] NSLIJHS Hofstra North Shore LIJ Sch Med Program, Dept Pathol & Lab Med, New Hyde Pk, NY 11042 USA
[2] NSLIJHS Hofstra North Shore LIJ Sch Med Program, Dept OBS GYN Oncol, New Hyde Pk, NY 11042 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA
来源：
ANNALS OF CLINICAL AND LABORATORY SCIENCE | 2015年 / 45卷 / 03期
关键词：
Sertoli-Leydig cell tumor; sex cord stromal tumor; heterologous elements; SERUM ALPHA-FETOPROTEIN; CLINICOPATHOLOGICAL ANALYSIS; GASTROINTESTINAL EPITHELIUM; RETIFORM; ANDROBLASTOMA; ELEMENT;
D O I：
暂无
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Sertoli-Leydig cell tumor is a rare ovarian neoplasm and belongs to the group of sex cord stromal tumors. We present a case of a 15-year old girl diagnosed with Sertoli-Leydig cell tumor with heterologous elements consisting predominantly of mucinous epithelium and a sparse Sertoli-Leydig cell component, mimicking mucinous neoplasm. Furthermore, foci of hepatocytic differentiation were also identified. Immunohistochemical stains showed the component of Sertoli cell differentiation was positive for cytokeratin 18 and inhibin. The component of Leydig cell differentiation was strongly positive for inhibin. The component of hepatocytic differentiation was positive for low molecular weight keratin, HepPar1, alpha-fetoprotein and weakly positive for inhibin. Thus, this was a very rare case which created a challenge for pathologists, especially on frozen sections.
引用
收藏
页码：348 / 351
页数：4
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