Adaptive response in frogs chronically exposed to low doses of ionizing radiation in the environment

被引：35

作者：

Audette-Stuart, M. ^{[1
]}

Kim, S. B. ^{[1
]}

McMullin, D. ^{[1
]}

Festarini, A. ^{[1
]}

Yankovich, T. L. ^{[1
]}

Carr, J. ^{[1
]}

Mulpuru, S. ^{[1
]}

机构：

[1] Atom Energy Canada Ltd, Chalk River Labs, Environm Technol Branch, Chalk River, ON K0J 1P0, Canada

来源：

JOURNAL OF ENVIRONMENTAL RADIOACTIVITY | 2011年 / 102卷 / 06期

关键词：

Ionizing radiation; Adaptive response; Micronucleus assay; HUMAN-LYMPHOCYTES; RESISTANCE; APOPTOSIS;

D O I：

10.1016/j.jenvrad.2011.03.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Using the micronucleus assay, decreased levels of DNA damage were found after high dose ionizing radiation exposure of liver cells taken from frogs inhabiting a natural environment with above-background levels of ionizing radiation, compared to cells taken from frogs inhabiting background areas. The data obtained from a small number of animals suggest that stress present in the above-background environment could induce an adaptive response to ionizing radiation. This study did not reveal harmful effects of exposure to low levels of radioactivity. On the contrary, stress present in the above-background area may serve to enhance cellular defense mechanisms. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.

引用

页码：566 / 573

页数：8