A mini-review on peptide-based self-assemblies and their biological applications

被引:17
作者
Wang, Chenlei [1 ]
Fu, Linping [1 ,2 ]
Hu, Zhiyuan [1 ]
Zhong, Yeteng [1 ,2 ]
机构
[1] Chinese Acad Sci, Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
关键词
self-assembly; peptide-based architecture; nanostructure regulation; biological applications; PH; CELL; NANOSTRUCTURES; NANOTUBES; NANOPARTICLES; NANOFIBERS; HYDROGELS; POLYMERS; RELEASE; DESIGN;
D O I
10.1088/1361-6528/ac2fe3
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Peptide-based supramolecular self-assembly from peptide monomers into well-organized nanostructures, has attracted extensive attentions towards biomedical and biotechnological applications in recent decades. This spontaneous and reversible assembly process involving non-covalent bonding interactions can be artificially regulated. In this review, we have elaborated different strategies to modulate the peptide self-assembly through tuning the physicochemical and environmental conditions, including pH, light, temperature, solvent, and enzyme. Detailed introduction of biological applications and future potential of the peptide-based nano-assemblies will also be given.
引用
收藏
页数:13
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