Cognitive function and falling among older adults with mild cognitive impairment and slow gait

被引:62
作者
Doi, Takehiko [1 ,2 ,3 ]
Shimada, Hiroyuki [1 ]
Park, Hyuntae [1 ]
Makizako, Hyuma [1 ,2 ,3 ]
Tsutsumimoto, Kota [1 ]
Uemura, Kazuki [1 ,3 ]
Nakakubo, Sho [1 ]
Hotta, Ryo [1 ]
Suzuki, Takao [2 ]
机构
[1] Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Dept Functioning Activat, Obu, Aichi 4748511, Japan
[2] Natl Ctr Geriatr & Gerontol, Res Inst, Obu, Aichi 4748511, Japan
[3] Japan Soc Promot Sci, Tokyo, Japan
关键词
cognition; elderly; gait; mild cognitive impairment; neuropsychological assessment; RISK; DEMENTIA; FRAILTY; PEOPLE; SPEED; ASSOCIATION; DYSFUNCTION; PREDICTOR; DECLINE;
D O I
10.1111/ggi.12407
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
AimTo examine the association of the combination of slow gait and mild cognitive impairment (MCI) with cognitive function and falling in community-dwelling older people. MethodsParticipants were selected from the Obu Study of Health Promotion for the Elderly (n=3400), and underwent gait examination and a battery of neuropsychological examinations, including the Mini-Mental State Examination and the National Center for Geriatrics and Gerontology Functional Assessment Tool (tablet version of Trail Making Test Part A and B, Symbol Digit Substitution Task, Figure selection task, Word memory and Story memory), and were interviewed with a series of questionnaires including medical history, physical activity, geriatric depression scale and fall history. ResultsParticipants were classified into control (n=2281), slow gait speed (SG; n=278), MCI (n=673) and MCI with SG (MCI+SG; n=168) groups. All cognitive functions were significantly affected by the group factor, even adjusting for participant characteristics as covariates (P<0.001). Post-hoc analysis showed that the control group had better performance than the other groups, and the MCI+SG group had worse performance than the other groups in all cognitive functions (all P<0.05). In multiple logistic regression analysis, SG and MCI were independently associated with falling (all P<0.05), and MCI+SG had a higher odds ratio for falling (adjusted OR 1.99, 95% CI 1.08-3.65). ConclusionsOur findings support the idea that slow gait and MCI were related, and concurrently associated with falling. Motor function among MCI subjects should be focused on to assess profile risks. Geriatr Gerontol Int 2015; 15: 1073-1078.
引用
收藏
页码:1073 / 1078
页数:6
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