Copper-catalyzed ortho-halogenation of arenes and heteroarenes directed by a removable auxiliary

被引：89

作者：

Li, Bo ^{[1
]}

Liu, Bin ^{[1
]}

Shi, Bing-Feng ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 24期

关键词：

C-H BONDS; CROSS-COUPLING REACTIONS; CARBON-HYDROGEN BONDS; OXIDATIVE FUNCTIONALIZATION; KINETIC RESOLUTION; C(SP(3))-H BONDS; PALLADIUM; IODINATION; ACTIVATION; HALIDES;

D O I：

10.1039/c5cc00531k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper-catalyzed ortho-halogenation of C(sp(2))-H bonds directed by a PIP directing group with NXS (X = Cl, Br, I) has been developed. The reaction is scalable and tolerates a broad range of functional groups and heteroarenes, providing an efficient access to halogenated arenes and heteroarenes.

引用

页码：5093 / 5096

页数：4

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