Copper-catalyzed ortho-halogenation of arenes and heteroarenes directed by a removable auxiliary

被引：89
作者：
Li, Bo [1 ]
Liu, Bin [1 ]
Shi, Bing-Feng [1 ,2 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 24期
关键词：
C-H BONDS; CROSS-COUPLING REACTIONS; CARBON-HYDROGEN BONDS; OXIDATIVE FUNCTIONALIZATION; KINETIC RESOLUTION; C(SP(3))-H BONDS; PALLADIUM; IODINATION; ACTIVATION; HALIDES;
D O I：
10.1039/c5cc00531k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Copper-catalyzed ortho-halogenation of C(sp(2))-H bonds directed by a PIP directing group with NXS (X = Cl, Br, I) has been developed. The reaction is scalable and tolerates a broad range of functional groups and heteroarenes, providing an efficient access to halogenated arenes and heteroarenes.
引用
收藏
页码：5093 / 5096
页数：4
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