Solubility of ceftriaxone disodium in acetone, methanol, ethanol, N,N-dimethylformamide, and formamide between 278 and 318 K

被引：23

作者：

Zhang, CT ^{[1
]}

Wang, JK ^{[1
]}

Wang, YL ^{[1
]}

机构：

[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2005年 / 50卷 / 05期

关键词：

D O I：

10.1021/je0501989

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

Experimental results are reported for the solubility of ceftriaxone disodium in acetone, methanol, ethanol, formamide, and N,N-dimethylformamide between 278 and 318 K. The isothermal method and the laser monitoring observation technique were used for the determination of the mole fraction concentration. The solubility of ceftriaxone disodium in pure solvents increases with increasing temperature and in the following order: acetone < ethanol < N,N-dimethylformamide < methanol < formamide. The experimental solubility data were correlated with a semiempirical equation.

引用

页码：1757 / 1760

页数：4

共 14 条

[1]

Broul M., 1981, SOLUBILITY INORGANIC

[2]

Cheng NL, 2002, SOLVENT HDB

[3] Solubility and density of the disodium salt hemiheptahydrate of ceftriaxone in (acetone plus water) at T = (298.15,308.15, and 318.15) K [J].

Dong, H ;

Fu, RR ;

Yan, WD ;

Zhu, M .

JOURNAL OF CHEMICAL THERMODYNAMICS, 2004, 36 (02) :155-159

[4] Solubility and density,of the disodium salt hemiheptahydrate of ceftriaxone in water plus methanol mixtures [J].

Fu, RR ;

Yan, WD ;

Zhu, M .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2004, 49 (02) :262-263

[5]

Grant D., 1990, SOLUBILITY BEHAV ORG

[6] Solubility of dexamethasone sodium phosphate in different solvents [J].

Hao, HX ;

Wang, JK ;

Wang, YL .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2004, 49 (06) :1697-1698

[7]

Hefter G.T., 2003, The Experimental Determination of Solubilities

[8] Solid-liquid equilibria for benzoic acid plus p-toluic acid plus chloroform, benzoic acid plus p-toluic acid plus acetic acid, and terephthalic acid plus isophthalic acid plus N,N-dimethylformamide [J].

Li, DQ ;

Lin, YJ ;

Evans, DG ;

Duan, X .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2005, 50 (01) :119-121

[9] Robust identification and control of batch processes [J].

Ma, DL ;

Braatz, RD .

COMPUTERS & CHEMICAL ENGINEERING, 2003, 27 (8-9) :1175-1184

[10]

PAN J, 2003, HUAXUE GONGYE YU GON, V20, P337

← 1 2 →