Electrophotocatalytic C-H Hydroxyalkylation of Heteroaromatics with Aldehydes

被引：22

作者：

Bi, Huihua ^{[1
]}

Zhou, Yu ^{[1
]}

Jiang, Wei ^{[1
]}

Liu, Jie ^{[1
,2
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Biomacromol Chem Biol, Changsha 410082, Hunan, Peoples R China

[2] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2022年 / 364卷 / 10期

关键词：

Electrophotocatalysis; Hydroxyalkylation; Minisci reaction; Radical coupling; Heteroaromatics; DECATUNGSTATE ANION; MINISCI REACTION; FUNCTIONALIZATION; ELECTROCHEMISTRY; PHOTOCATALYSIS; SUBSTITUTIONS; GREEN;

D O I：

10.1002/adsc.202200055

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Herein a radical hydroxyalkylation of N-heteroaromatics with aldehydes is reported. The constructive merging of photochemistry and electrochemistry is the key for the success of this atom-economical Minisci method. This protocol highlights the utility of electrophotocatalysis to promote a practical and general synthesis of secondary alcohols in good yields from readily available N-heteroaromatics and aldehydes under mild reaction condition.

引用

页码：1732 / 1737

页数：6

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