Rhodium-catalyzed ortho-C-H olefination of aromatic aldehydes employing transient directing strategy

被引：9

作者：

Liu, Xi

Wang, Zhonghao

Chen, Qun

He, Ming-yang ^{[1
,2
]}

Wang, Liang ^{[1
,2
]}

机构：

[1] Changzhou Univ, Sch Petrochem Engn, Changzhou 213164, Peoples R China

[2] Changzhou Univ, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2018年 / 32卷 / 02期

基金：

中国国家自然科学基金;

关键词：

aryl aldehydes; C-H activation; olefination; transient directing groups; BOND ACTIVATION; PRIMARY AMINES; ARYLATION; FUNCTIONALIZATION; KETONES; HYDROACYLATION; BENZALDEHYDES; SUBSTITUTION; ALKYLATION;

D O I：

10.1002/aoc.4039

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A Rhodium(III)-catalyzed ortho-C-H olefination of aromatic aldehydes in the presence of catalytic amount of TsNH2 has been developed. The in situ generated imine intermediate from aldehyde and TsNH2 worked as a transient directing group. Both electron-rich and electron-deficient aromatic aldehydes were tolerated, affording the corresponding products in moderate to good yields. Importantly, the present protocol provides a straightforward access to olefinated aromatic aldehydes with aldehydes as the simple starting materials.

引用

页数：7

共 48 条

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