A novel approach for the synthesis of highly fluorescent pyrrolo[1,2-b]pyridazines

被引:24
作者
Dumitrascu, Florea [2 ]
Caira, Mino R. [1 ]
Draghici, Bogdan [2 ]
Caproiu, Miron Teodor [2 ]
Dumitrescu, Dan G. [2 ]
机构
[1] Univ Cape Town, Dept Chem, ZA-7701 Rondebosch, South Africa
[2] Acad Romana, Ctr Organ Chem CD Nenitzescu, Bucharest 060023, Romania
关键词
1,3-dipolar cycloaddition; mesoionic oxazolopyridazine; pyrrolo[1,2-b]pyridazines; Michael addition; hydrogenation;
D O I
10.1055/s-2008-1042929
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pyrrolo[1,2-b]pyridazine derivatives were synthesized for the first time by 1,3-dipolar cycloaddition reaction between mesoionic 1,3-oxazolo[3,2-b]pyridazinium-2-oxides and acetylenic dipolarophiles. The isolation and characterization of the stable mesoionic oxazolo[3,2-b]pyridazines are also presented.
引用
收藏
页码:813 / 816
页数:4
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