Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature

被引：2

作者：

Lane-Donovan, Courtney ^{[1
]}

Bainbridge, Emma ^{[2
,3
]}

Szumowski, John ^{[2
,3
]}

Kerkhoff, Andrew D. ^{[2
,3
]}

Peluso, Michael J. ^{[2
,3
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

[2] Univ Calif San Francisco, Dept Med, Zuckerberg San Francisco Gen Hosp, Div HIV Infect Dis & Global Med, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Trauma Ctr, San Francisco, CA 94143 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2021年 / 8卷 / 11期

基金：

美国国家卫生研究院;

关键词：

HIV; IRIS; MAC; space-occupying lesion; universal broad-range PCR; RECONSTITUTION INFLAMMATORY SYNDROME; SPINDLE-CELL PSEUDOTUMOR; CENTRAL-NERVOUS-SYSTEM; IMMUNE RECONSTITUTION; BRAIN-ABSCESS; THERAPY; INITIATION;

D O I：

10.1093/ofid/ofab450

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially treated infections.

引用

页数：7

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