Nasopharyngeal adenoid cystic carcinoma, a rare but highly challenging disease with unmet therapeutic needs: A case-report and review of the literature

被引：8
作者：
Afani, L. [1 ]
Errihani, H. [2 ]
Benchafai, I. [3 ]
Lalami, Y. [1 ]
机构：
[1] Inst Jules Bordet, Serv Oncol Med, Blvd Waterloo,121, B-1000 Brussels, Belgium
[2] Inst Natl Oncol, Serv Oncol Med, BP 6213 RI, Rabat, Morocco
[3] Hop Mil Instruct Mohammed V, Serv ORL, Rabat, Morocco
来源：
CANCER RADIOTHERAPIE | 2016年 / 20卷 / 05期
关键词：
Adenoid cystic carcinoma; Nasopharynx; Radiotherapy; Hadrontherapy; CARBON ION BOOST; RADIATION-THERAPY; HEAD; NECK; RADIOTHERAPY; CHEMOTHERAPY; OUTCOMES;
D O I：
10.1016/j.canrad.2015.12.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Nasopharyngeal adenoid cystic carcinoma is a rare tumour. Compared with others nasopharyngeal tumours, it is characterised by slow evolution but it is locally aggressive and has a high tendency to recurrences. Due to the rarity of cases, no consensus exists about treatment approaches. We report the case of 45-year-old-man with a locally advanced adenoid cystic carcinoma. The patient received concurrent chemoradiation and had a good objective response. After one year, he developed a paucisymptomatic lung metastasis. The follow-up showed local recurrence after 3 years. One cycle of chemotherapy was given but poorly supported. Carbon ion radiotherapy was proposed. The aim of this work is to review the literature concerning this rare malignancy and discusses treatment approaches in initial situations and during recurrences. (C) 2016 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：400 / 404
页数：5
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