Primary Sjogren's syndrome and the eye

被引：123

作者：

Bjordal, Oddbjorn ^{[1
]}

Norheim, Katrine Braekke ^{[2
]}

Rodahl, Eyvind ^{[3
,4
]}

Jonsson, Roland ^{[5
,6
]}

Omdal, Roald ^{[2
,5
]}

机构：

[1] Ostfold Hosp, Dept Ophthalmol, Gralum, Norway

[2] Stavanger Univ Hosp, Dept Internal Med, Clin Immunol Unit, POB 8100, N-4068 Stavanger, Norway

[3] Haukeland Hosp, Dept Ophthalmol, Bergen, Norway

[4] Univ Bergen, Dept Clin Med, Bergen, Norway

[5] Univ Bergen, Dept Clin Sci, Broegelmann Res Lab, Bergen, Norway

[6] Haukeland Hosp, Dept Rheumatol, Bergen, Norway

来源：

SURVEY OF OPHTHALMOLOGY | 2020年 / 65卷 / 02期

基金：

欧盟地平线“2020”;

关键词：

primary Sjogren syndrome; dry eye disease; treatment; lacrimal gland; inflammation; SYNDROME DRY EYE; EPSTEIN-BARR-VIRUS; SCANNING CONFOCAL MICROSCOPY; OCULAR SURFACE DISEASE; LABIAL SALIVARY-GLANDS; LACRIMAL GLANDS; CLASSIFICATION CRITERIA; KERATOCONJUNCTIVITIS SICCA; ARTIFICIAL TEARS; LYMPHOID ORGANIZATION;

D O I：

10.1016/j.survophthal.2019.10.004

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Primary Sjogren syndrome is an autoimmune disease that mainly affects exocrine glands such as the salivary and lacrimal glands. In addition, systemic involvement is common. Primary Sjogren syndrome is of particular interest to ophthalmologists as it constitutes an important differential diagnosis in conditions with dry eye disease. In addition, ocular tests for more precisely diagnosing and monitoring primary Sjogren syndrome have become increasingly important, and new therapeutics for local and systemic treatment evolve as a result of increased understanding of immunological mechanisms and molecular pathways in the pathogenesis of primary Sjogren syndrome. We provide an update of interest to ophthalmologists regarding pathogenesis, diagnosis, investigative procedures, and treatment options. (C) 2019 The Author(s). Published by Elsevier Inc.

引用

页码：119 / 132

页数：14

共 147 条

[1] ACETYLCYSTEINE IN KERATO-CONJUNCTIVITIS SICCA [J].