Reduction of olefins on solid support using diimide

被引：25

作者：

Lacombe, P ^{[1
]}

Castagner, B ^{[1
]}

Gareau, Y ^{[1
]}

Ruel, R ^{[1
]}

机构：

[1] Merck Frosst Ctr Therapeut Res, Pointe Claire, PQ H9R 4P8, Canada

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(98)01490-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reduction of solid supported olefinic substrate using diimide is described. The diimide, prepared from sulfonylhydrazide, was found to efficiently reduce the olefinic substrates. Typically, the reaction proceeds in over 90% yield to afford the reduction product cleanly after cleavage from the Wang resin. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6785 / 6786

页数：2

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