Cloning, Polymorphism and Tissue Expression of TAC3 Gene in Sheep

被引：2

作者：

Hu, Wenping ^{[1
]}

Wang, Xiangyu ^{[1
]}

Sun, Xiaodi ^{[2
]}

Di, Ran ^{[1
]}

Liu, Qiuyue ^{[1
]}

Pan, Zhangyuan ^{[1
]}

Guo, Xiaofei ^{[1
]}

Cao, Xiaohan ^{[1
]}

Wang, Jinyu ^{[2
]}

Zhang, Yingjie ^{[3
]}

Jin, Mei ^{[4
]}

Yang, Yuze ^{[5
]}

Chu, Mingxing ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Inst Anim Sci, Beijing 100193, Peoples R China

[2] Yangzhou Univ, Coll Anim Sci & Technol, Yangzhou 225009, Jiangsu, Peoples R China

[3] Hebei Agr Univ, Coll Anim Sci & Technol, Baoding 071000, Peoples R China

[4] Liaoning Normal Univ, Coll Life Sci, Dalian 116029, Peoples R China

[5] Beijing Gen Stn Anim Husb, Beijing 100101, Peoples R China

来源：

PAKISTAN JOURNAL OF ZOOLOGY | 2020年 / 52卷 / 04期

基金：

中国国家自然科学基金;

关键词：

TAC3; gene; Small Tail Han sheep; Tan sheep; Polymorphism; Tissue expression; NEUROKININ-B; TACHYKININS; SECRETION; NEURONS;

D O I：

10.17582/journal.pjz/20170303090335

中图分类号：

Q95 [动物学];

学科分类号：

071002 ;

摘要：

TAC3 gene is related to the regulation of animal reproductive function. Here we tried to find out the association of the expression and polymorphism of TAC3 gene with the estrus of sheep. TAC3 expression in uterus and pituitary gland increased in estrus of Small Tail Han sheep and Tan sheep. The TAC3 expression level in uterus might relate with estrus of sheep. Two mutations of TAC3 were found in intron 1 (C327T) and exon 2 (G1803A) separately. Although there were significant differences of C327T/G1803A genotype distributions in five different sheep breeds, it did not relate with the year-round estrus. The relationship between these polymorphisms of TAC3 and the litter size of Small Tail Han sheep was not found.

引用

页码：1541 / 1546

页数：6

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