Allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning regimen for elderly patients (60 years and older) with hematologic malignancies using unrelated donors: a retrospective study from the French society for stem cell transplantation (SFGM-TC)

被引:4
作者
El Cheikh, Jean [1 ]
Sfumato, Patrick [2 ]
Sobh, Mohamad [3 ]
Fegueux, Nathalie [4 ]
Mohty, Mohamad [5 ]
Vigouroux, Stephane [6 ,7 ]
Beguin, Yves [8 ]
Yakoub-Agha, Ibrahim [9 ]
Socie, Gerard [10 ]
Cornillon, Jerome [11 ]
Mercier, Melanie [12 ]
Bay, Jacques Olivier [13 ]
Blaise, Didier [14 ]
Michallet, Mauricette [3 ]
de latour, Regis Peffault [10 ]
机构
[1] Amer Univ Beirut, Med Ctr Beirut, Hematol & Oncol Bone Marrow Transplantat Program, Beirut, Lebanon
[2] Paoli Calmettes Inst, Clin Trial Off & Biostat Unit, Marseille, France
[3] Univ Hosp Ctr, Dept Hematol, Lyon, France
[4] Univ Hosp Ctr, Dept Hematol, Montpellier, France
[5] Univ Paris 06, Hop St Antoine, AP HP, Hematol & Cellular Therapy Unit, Paris, France
[6] Haut Leveque Hosp, Dept Hematol, Pessac, France
[7] Bordeaux Univ, Ctr Hosp, Pessac, France
[8] Univ Liege, Ctr Hosp Univ Liege, Dept Hematol, Liege, Belgium
[9] Univ Hosp Ctr, Dept Hematol, Lille, France
[10] Hop St Antoine, AP HP, Hematol & Cellular Therapy Unit, Paris, France
[11] St Etienne Univ Hosp, Dept Hematol, St Etienne, France
[12] Univ Hosp Ctr, Dept Hematol, Angers, France
[13] Univ Hosp Ctr, Dept Hematol, Clermont Ferrand, France
[14] Paoli Calmettes Inst, Dept Hematol, Transplantat Unit, Marseille, France
关键词
allogeneic stem cell transplantation; elderly patients; unrelated donors; ACUTE MYELOID-LEUKEMIA; MYELODYSPLASTIC SYNDROME; BUSULFAN; FLUDARABINE; RELAPSE; TRIAL;
D O I
10.3324/haematol.2015.139345
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E262 / E265
页数:4
相关论文
共 9 条
  • [1] Defining the Intensity of Conditioning Regimens: Working Definitions
    Bacigalupo, Andrea
    Ballen, Karen
    Rizzo, Doug
    Giralt, Sergio
    Lazarus, Hillard
    Ho, Vincent
    Apperley, Jane
    Slavin, Shimon
    Pasquini, Marcelo
    Sandmaier, Brenda M.
    Barrett, John
    Blaise, Didier
    Lowski, Robert
    Horowitz, Mary
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (12) : 1628 - 1633
  • [2] Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial
    Blaise, Didier
    Devillier, Raynier
    Lecoroller-Sorriano, Anne-Gaelle
    Boher, Jean-Marie
    Boyer-Chammard, Agnes
    Tabrizi, Reza
    Chevallier, Patrice
    Fegueux, Nathalie
    Sirvent, Anne
    Michallet, Mauricette
    Bay, Jacques-Olivier
    Fuerst, Sabine
    El-Cheikh, Jean
    Vincent, Laure
    Guillaume, Thierry
    Regny, Caroline
    Milpied, Noel
    Castagna, Luca
    Mohty, Mohamad
    [J]. HAEMATOLOGICA, 2015, 100 (02) : 269 - 274
  • [3] Busulfan Dose Intensity and Outcomes in Reduced-Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for Myelodysplastic Syndrome or Acute Myeloid Leukemia
    Chen, Yi-Bin
    Coughlin, Erin
    Kennedy, Kevin F.
    Alyea, Edwin P.
    Armand, Philippe
    Attar, Eyal C.
    Ballen, Karen K.
    Cutler, Corey
    Dey, Bimalangshu R.
    Koreth, John
    McAfee, Steven L.
    Spitzer, Thomas R.
    Antin, Joseph H.
    Soiffer, Robert J.
    Ho, Vincent T.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (06) : 981 - 987
  • [4] Reduced-Intensity Conditioning before Allogeneic Hematopoietic Stem Cell Transplantation in Patients Over 60 Years: A Report from the SFGM-TC
    Chevallier, Patrice
    Szydlo, Richard M.
    Blaise, Didier
    Tabrizi, Reza
    Michallet, Mauricette
    Uzunov, Madalina
    Fegueux, Nathalie
    Guilhot, Francois
    Lapusan, Simona
    Gratecos, Nicole
    Cohn, Jean-Yves
    Socie, Gerard
    Yakoub-Agha, Ibrahim
    Huynh, Anne
    Francois, Sylvie
    Bay, Jacques-Olivier
    Maury, Sebastien
    Buzyn, Agnes
    Contentin, Nathalie
    Mohty, Mohamad
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) : 289 - 294
  • [5] A conditioning platform based on fludarabine, busulfan, and 2 days of rabbit antithymocyte globulin results in promising results in patients undergoing allogeneic transplantation from both matched and mismatched unrelated donor
    Devillier, Raynier
    Fuerst, Sabine
    Crocchiolo, Roberto
    El-Cheikh, Jean
    Castagna, Luca
    Harbi, Samia
    Granata, Angela
    D'Incan, Evelyne
    Coso, Diane
    Chabannon, Christian
    Picard, Christophe
    Etienne, Anne
    Calmels, Boris
    Schiano, Jean-Marc
    Lemarie, Claude
    Stoppa, Anne-Marie
    Bouabdallah, Reda
    Vey, Norbert
    Blaise, Didier
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 2014, 89 (01) : 83 - 87
  • [6] Use of Matched Unrelated Donors Compared with Matched Related Donors Is Associated with Lower Relapse and Superior Progression-Free Survival after Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation
    Ho, Vincent T.
    Kim, Haesook T.
    Aldridge, Julie
    Liney, Deborah
    Kao, Grace
    Armand, Philippe
    Koreth, John
    Cutler, Corey
    Ritz, Jerome
    Antin, Joseph H.
    Soiffer, Robert J.
    Alyea, Edwin P.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2011, 17 (08) : 1196 - 1204
  • [7] Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation in Patients Over 60 Years: Hematologic Malignancy Outcomes Are Not Impaired in Advanced Age
    Koreth, John
    Aldridge, Julie
    Kim, Haesook T.
    Alyea, Edwin P., III
    Cutler, Corey
    Armand, Philippe
    Ritz, Jerome
    Antin, Joseph H.
    Soiffer, Robert J.
    Ho, Vincent T.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (06) : 792 - 800
  • [8] Effect of Age on Outcome of Reduced-Intensity Hematopoietic Cell Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission or With Myelodysplastic Syndrome
    McClune, Brian L.
    Weisdorf, Daniel J.
    Pedersen, Tanya L.
    Tunes da Silva, Gisela
    Tallman, Martin S.
    Sierra, Jorge
    DiPersio, John
    Keating, Armand
    Gale, Robert P.
    George, Biju
    Gupta, Vikas
    Hahn, Theresa
    Isola, Luis
    Jagasia, Madan
    Lazarus, Hillard
    Marks, David
    Maziarz, Richard
    Waller, Edmund K.
    Bredeson, Chris
    Giralt, Sergio
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (11) : 1878 - 1887
  • [9] Reduced-Toxicity Conditioning With Fludarabine, Once-Daily Intravenous Busulfan, and Antithymocyte Globulins Prior to Allogeneic Stem Cell Transplantation: Results of a Multicenter Prospective Phase 2 Trial
    Mohty, Mohamad
    Malard, Florent
    Blaise, Didier
    Milpied, Noel
    Furst, Sabine
    Tabrizi, Resa
    Guillaume, Thierry
    Vigouroux, Stephane
    El-Cheikh, Jean
    Delaunay, Jacques
    Le Gouill, Steven
    Moreau, Philippe
    Labopin, Myriam
    Chevallier, Patrice
    [J]. CANCER, 2015, 121 (04) : 562 - 569