Allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning regimen for elderly patients (60 years and older) with hematologic malignancies using unrelated donors: a retrospective study from the French society for stem cell transplantation (SFGM-TC)

被引:4
作者
El Cheikh, Jean [1 ]
Sfumato, Patrick [2 ]
Sobh, Mohamad [3 ]
Fegueux, Nathalie [4 ]
Mohty, Mohamad [5 ]
Vigouroux, Stephane [6 ,7 ]
Beguin, Yves [8 ]
Yakoub-Agha, Ibrahim [9 ]
Socie, Gerard [10 ]
Cornillon, Jerome [11 ]
Mercier, Melanie [12 ]
Bay, Jacques Olivier [13 ]
Blaise, Didier [14 ]
Michallet, Mauricette [3 ]
de latour, Regis Peffault [10 ]
机构
[1] Amer Univ Beirut, Med Ctr Beirut, Hematol & Oncol Bone Marrow Transplantat Program, Beirut, Lebanon
[2] Paoli Calmettes Inst, Clin Trial Off & Biostat Unit, Marseille, France
[3] Univ Hosp Ctr, Dept Hematol, Lyon, France
[4] Univ Hosp Ctr, Dept Hematol, Montpellier, France
[5] Univ Paris 06, Hop St Antoine, AP HP, Hematol & Cellular Therapy Unit, Paris, France
[6] Haut Leveque Hosp, Dept Hematol, Pessac, France
[7] Bordeaux Univ, Ctr Hosp, Pessac, France
[8] Univ Liege, Ctr Hosp Univ Liege, Dept Hematol, Liege, Belgium
[9] Univ Hosp Ctr, Dept Hematol, Lille, France
[10] Hop St Antoine, AP HP, Hematol & Cellular Therapy Unit, Paris, France
[11] St Etienne Univ Hosp, Dept Hematol, St Etienne, France
[12] Univ Hosp Ctr, Dept Hematol, Angers, France
[13] Univ Hosp Ctr, Dept Hematol, Clermont Ferrand, France
[14] Paoli Calmettes Inst, Dept Hematol, Transplantat Unit, Marseille, France
关键词
allogeneic stem cell transplantation; elderly patients; unrelated donors; ACUTE MYELOID-LEUKEMIA; MYELODYSPLASTIC SYNDROME; BUSULFAN; FLUDARABINE; RELAPSE; TRIAL;
D O I
10.3324/haematol.2015.139345
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E262 / E265
页数:4
相关论文
共 9 条
[1]   Defining the Intensity of Conditioning Regimens: Working Definitions [J].
Bacigalupo, Andrea ;
Ballen, Karen ;
Rizzo, Doug ;
Giralt, Sergio ;
Lazarus, Hillard ;
Ho, Vincent ;
Apperley, Jane ;
Slavin, Shimon ;
Pasquini, Marcelo ;
Sandmaier, Brenda M. ;
Barrett, John ;
Blaise, Didier ;
Lowski, Robert ;
Horowitz, Mary .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (12) :1628-1633
[2]   Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial [J].
Blaise, Didier ;
Devillier, Raynier ;
Lecoroller-Sorriano, Anne-Gaelle ;
Boher, Jean-Marie ;
Boyer-Chammard, Agnes ;
Tabrizi, Reza ;
Chevallier, Patrice ;
Fegueux, Nathalie ;
Sirvent, Anne ;
Michallet, Mauricette ;
Bay, Jacques-Olivier ;
Fuerst, Sabine ;
El-Cheikh, Jean ;
Vincent, Laure ;
Guillaume, Thierry ;
Regny, Caroline ;
Milpied, Noel ;
Castagna, Luca ;
Mohty, Mohamad .
HAEMATOLOGICA, 2015, 100 (02) :269-274
[3]   Busulfan Dose Intensity and Outcomes in Reduced-Intensity Allogeneic Peripheral Blood Stem Cell Transplantation for Myelodysplastic Syndrome or Acute Myeloid Leukemia [J].
Chen, Yi-Bin ;
Coughlin, Erin ;
Kennedy, Kevin F. ;
Alyea, Edwin P. ;
Armand, Philippe ;
Attar, Eyal C. ;
Ballen, Karen K. ;
Cutler, Corey ;
Dey, Bimalangshu R. ;
Koreth, John ;
McAfee, Steven L. ;
Spitzer, Thomas R. ;
Antin, Joseph H. ;
Soiffer, Robert J. ;
Ho, Vincent T. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (06) :981-987
[4]   Reduced-Intensity Conditioning before Allogeneic Hematopoietic Stem Cell Transplantation in Patients Over 60 Years: A Report from the SFGM-TC [J].
Chevallier, Patrice ;
Szydlo, Richard M. ;
Blaise, Didier ;
Tabrizi, Reza ;
Michallet, Mauricette ;
Uzunov, Madalina ;
Fegueux, Nathalie ;
Guilhot, Francois ;
Lapusan, Simona ;
Gratecos, Nicole ;
Cohn, Jean-Yves ;
Socie, Gerard ;
Yakoub-Agha, Ibrahim ;
Huynh, Anne ;
Francois, Sylvie ;
Bay, Jacques-Olivier ;
Maury, Sebastien ;
Buzyn, Agnes ;
Contentin, Nathalie ;
Mohty, Mohamad .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) :289-294
[5]   A conditioning platform based on fludarabine, busulfan, and 2 days of rabbit antithymocyte globulin results in promising results in patients undergoing allogeneic transplantation from both matched and mismatched unrelated donor [J].
Devillier, Raynier ;
Fuerst, Sabine ;
Crocchiolo, Roberto ;
El-Cheikh, Jean ;
Castagna, Luca ;
Harbi, Samia ;
Granata, Angela ;
D'Incan, Evelyne ;
Coso, Diane ;
Chabannon, Christian ;
Picard, Christophe ;
Etienne, Anne ;
Calmels, Boris ;
Schiano, Jean-Marc ;
Lemarie, Claude ;
Stoppa, Anne-Marie ;
Bouabdallah, Reda ;
Vey, Norbert ;
Blaise, Didier .
AMERICAN JOURNAL OF HEMATOLOGY, 2014, 89 (01) :83-87
[6]   Use of Matched Unrelated Donors Compared with Matched Related Donors Is Associated with Lower Relapse and Superior Progression-Free Survival after Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation [J].
Ho, Vincent T. ;
Kim, Haesook T. ;
Aldridge, Julie ;
Liney, Deborah ;
Kao, Grace ;
Armand, Philippe ;
Koreth, John ;
Cutler, Corey ;
Ritz, Jerome ;
Antin, Joseph H. ;
Soiffer, Robert J. ;
Alyea, Edwin P. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2011, 17 (08) :1196-1204
[7]   Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation in Patients Over 60 Years: Hematologic Malignancy Outcomes Are Not Impaired in Advanced Age [J].
Koreth, John ;
Aldridge, Julie ;
Kim, Haesook T. ;
Alyea, Edwin P., III ;
Cutler, Corey ;
Armand, Philippe ;
Ritz, Jerome ;
Antin, Joseph H. ;
Soiffer, Robert J. ;
Ho, Vincent T. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (06) :792-800
[8]   Effect of Age on Outcome of Reduced-Intensity Hematopoietic Cell Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission or With Myelodysplastic Syndrome [J].
McClune, Brian L. ;
Weisdorf, Daniel J. ;
Pedersen, Tanya L. ;
Tunes da Silva, Gisela ;
Tallman, Martin S. ;
Sierra, Jorge ;
DiPersio, John ;
Keating, Armand ;
Gale, Robert P. ;
George, Biju ;
Gupta, Vikas ;
Hahn, Theresa ;
Isola, Luis ;
Jagasia, Madan ;
Lazarus, Hillard ;
Marks, David ;
Maziarz, Richard ;
Waller, Edmund K. ;
Bredeson, Chris ;
Giralt, Sergio .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (11) :1878-1887
[9]   Reduced-Toxicity Conditioning With Fludarabine, Once-Daily Intravenous Busulfan, and Antithymocyte Globulins Prior to Allogeneic Stem Cell Transplantation: Results of a Multicenter Prospective Phase 2 Trial [J].
Mohty, Mohamad ;
Malard, Florent ;
Blaise, Didier ;
Milpied, Noel ;
Furst, Sabine ;
Tabrizi, Resa ;
Guillaume, Thierry ;
Vigouroux, Stephane ;
El-Cheikh, Jean ;
Delaunay, Jacques ;
Le Gouill, Steven ;
Moreau, Philippe ;
Labopin, Myriam ;
Chevallier, Patrice .
CANCER, 2015, 121 (04) :562-569