Evidence-based evaluation of the occupational relevance of different delayed type sensitizations or allergens. Survey of occupational skin diseases

Evidence-based guidelines about the distribution of type IV allergens of the European standard series in different professions and its occupational relevance are missing. Based on published data, epidemiological investigations, work related knowledge about industrial processes, and allergen specific properties, recommendations are given about the clinical impact in the working environment for the following allergens: Acrylates/Methacrylates, Epoxy resins, Dichromate, Cobalt, Nickel, Formaldehyde, (Chlor-)Methylisothiazolone, p-Phenylendiamine, Colophony, Thiurame, Mercaptobenzothiazole, Dithiocarbamate, N-Isopropyl-N'-phenyl-p-phenylendiamine, Fragrance Mix, Composite Mix, and Neomycinsulfate. These recommendations might improve the clearance rate and allergological evaluation of the occupational relevance of different delayed type sensitizations or allergens.