In vivo replication of African swine fever virus (Malawi '83) in neutrophils

被引：0
作者：
Carrasco, L
GomezVillamandos, JC
Bautista, MJ
delasMulas, JM
Villeda, CJ
Wilkinson, PJ
Sierra, MA
机构：
[1] AUTONOMOUS UNIV MADRID, CTR BIOL MOLEC, E-28049 MADRID, SPAIN
[2] PIRBRIGHT LAB, INST ANIM HLTH, PIRBRIGHT, ENGLAND
来源：
VETERINARY RESEARCH | 1996年 / 27卷 / 01期
关键词：
pig; viral replication; African swine fever virus; neutrophil;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The presence of Virus replication centers in neutrophils from pigs inoculated with a highly virulent strain of African swine fever virus is described for the first time in vivo. Virus antigens were observed from 3 days post-inoculation (dpi) onwards by means of an immunohistochemical technique. At this time (3 dpi), transmission electron microscopy studies revealed the presence of large amounts of neutrophils in the vascular lumens. At 5 and 7 dpi, neutrophils with phagosomes frequently contained virus particles. In addition, within the cytoplasm of some mature and immature neutrophils, both viral particles and virus replication centers were observed at 5 and 7 dpi.
引用
收藏
页码：55 / 62
页数：8
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