Extractive spectrophotometric determination of fluconazale by ion-pair cornplex formation with bromocresol green

被引：3
作者：
Jalali, Fahimeh [1 ]
Rajabi, Mohammad J. [1 ]
机构：
[1] Razi Univ, Fac Sci, Dept Chem, Kermanshah, Iran
来源：
CHINESE JOURNAL OF CHEMISTRY | 2007年 / 25卷 / 09期
关键词：
fluconazole; solvent extraction; spectrophotometry; capsule; blood serum;
D O I：
10.1002/cjoc.200790241
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An extraction-spectrophotometric method for the determination of trace amounts of fluconazole was described. Fluconazole was effectively extracted as a I : I ion-pair complex with bromocresole green (BCG) at pH 3.0 into chloroform, followed by spectrophotometric determination at 420 run. Beer's law was obeyed over the range of 450 mu g center dot mL(-1) of fluconazole with a detection limit of 3.7 mu g center dot mL(-1). The method is simple, rapid and sensitive. The procedure was applied to the determination of fluconazole in pharmaceutical preparations as well as its recovery from a blood serum sample.
引用
收藏
页码：1300 / 1303
页数：4
相关论文
共 50 条
  • [1] Ion-Pair Extractive Spectrophotometric Assay of Terbinafine Hydrochloride in Pharmaceuticals and Spiked Urine Using Bromocresol Purple
    N. A. Salem Qarah
    K. Basavaiah
    N. Swamy
    Journal of Applied Spectroscopy, 2016, 83 : 694 - 702
  • [2] Ion-Pair Extractive Spectrophotometric Assay of Terbinafine Hydrochloride in Pharmaceuticals and Spiked Urine Using Bromocresol Purple
    Qarah, N. A. Salem
    Basavaiah, K.
    Swamy, N.
    JOURNAL OF APPLIED SPECTROSCOPY, 2016, 83 (04) : 694 - 702
  • [3] EXTRACTIVE SPECTROPHOTOMETRIC DETERMINATION OF KETOCONAZOLE, CLOTRIMAZOLE AND FLUCONAZOLE BY ION-PAIR COMPLEX FORMATION WITH BROMOTHYMOL BLUE AND PICRIC ACID
    Alizadeh, Nina
    Rezakhani, Zahra
    JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2012, 57 (02) : 1104 - 1108
  • [4] Spectrophotometric determination of chromium based on ion-pair formation
    Maheswari, V
    Balasubramanian, N
    CHEMIA ANALITYCZNA, 1996, 41 (04): : 569 - 576
  • [5] Ion-pair spectrophotometric determination of sparfloxacin
    Patel, Rakesh
    Kumar, Brijesh
    Shukla, Shiv Shankar
    Singh, Raghvendra
    Bhandari, Anil
    ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (01) : 381 - 384
  • [6] Spectrophotometric determination of plasma thiocyanate by formation of an ion-pair with methylene blue
    Laforge, M
    Roques, MG
    Galliot, M
    Levillain, P
    ANNALES DE BIOLOGIE CLINIQUE, 1995, 53 (10-11) : 539 - 541
  • [7] Spectrophotometric Determination of Clonidine Hydrochloride through the Formation of Ion-Pair Complex
    Guimaraes, Sandra S.
    Sousa, Giovana D.
    Grangeiro Junior, Severino
    Castelo Branco, Daniel M.
    Albuquerque, Miracy M.
    Leal, Leila B.
    Santana, Davi P.
    LATIN AMERICAN JOURNAL OF PHARMACY, 2012, 31 (08): : 1222 - 1225
  • [8] Spectrophotometric determination of enrofloxacin and pefloxacin through ion-pair complex formation
    Mostafa, S
    El-Sadek, M
    Alla, EA
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 28 (01) : 173 - 180
  • [9] Extractive spectrophotometric determination of five selected drugs by ion-pair complex formation with bromothymol blue in pure form and pharmaceutical preparations
    Nair, Sneha G.
    Shah, Jaivik V.
    Shah, Priyanka A.
    Sanyal, Mallika
    Shrivastav, Pranav S.
    COGENT CHEMISTRY, 2015, 1 (01):
  • [10] A New extractive spectrophotometric method for determination of rizatriptan dosage forms using bromocresol green
    Effat Souri
    Abbas Kaboodari
    Noushin Adib
    Massoud Amanlou
    DARU Journal of Pharmaceutical Sciences, 21
12345