Nuclear transcription factors in mammalian mitochondria

被引:86
作者
Leigh-Brown, Sarah [1 ,2 ]
Antonio Enriquez, Jose [3 ,4 ]
Odom, Duncan T. [1 ,2 ]
机构
[1] Li Ka Shing Ctr, Cambridge Res Inst, Cambridge CB2 0RE, England
[2] Univ Cambridge, Dept Oncol, Hutchison MRC Res Ctr, Cambridge CB2 0XZ, England
[3] Ctr Nacl Invest Cardiovasc, Madrid 28029, Spain
[4] Univ Zaragoza, Dept Bioquim, E-50009 Zaragoza, Spain
基金
欧洲研究理事会;
关键词
ELEMENT-BINDING PROTEIN; AMP RESPONSE ELEMENT; THYROID-HORMONE RECEPTORS; REGULATORY GENE-PRODUCT; IN-VIVO; COMPLEX-I; GLUCOCORTICOID RECEPTOR; LIVER MITOCHONDRIA; BRAIN MITOCHONDRIA; EXCISION-REPAIR;
D O I
10.1186/gb-2010-11-7-215
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nuclear transcription factors have been detected in mammalian mitochondria and may directly regulate mitochondrial gene expression. Emerging genomics techniques may overcome outstanding challenges in this field.
引用
收藏
页数:9
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