Non-insulin-dependent diabetes mellitus - A genetically programmed failure of the beta cell to compensate for insulin resistance

被引：462
作者：
Polonsky, KS
Sturis, J
Bell, GI
机构：
[1] UNIV CHICAGO,DEPT BIOCHEM,CHICAGO,IL 60637
[2] UNIV CHICAGO,DEPT MOLEC BIOL,CHICAGO,IL 60637
[3] UNIV CHICAGO,HOWARD HUGHES MED INST,CHICAGO,IL 60637
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 1996年 / 334卷 / 12期
关键词：
D O I：
10.1056/NEJM199603213341207
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：777 / 783
页数：7
相关论文
共 71 条
[41]   METABOLIC ABNORMALITIES IN CHILDREN OF NON-INSULIN-DEPENDENT DIABETICS [J].
LESLIE, RDG ;
VOLKMANN, HP ;
PONCHER, M ;
HANNING, I ;
ORSKOV, H ;
ALBERTI, KGMM .
BRITISH MEDICAL JOURNAL, 1986, 293 (6551) :840-842
[42]   IMPAIRED AUTOPHOSPHORYLATION OF INSULIN-RECEPTORS FROM ABDOMINAL SKELETAL-MUSCLES IN NONOBESE SUBJECTS WITH NIDDM [J].
MAEGAWA, H ;
SHIGETA, Y ;
EGAWA, K ;
KOBAYASHI, M .
DIABETES, 1991, 40 (07) :815-819
[43]   CIRCULATING PROINSULIN IN PATIENTS WITH MATURITY ONSET DIABETES [J].
MAKO, ME ;
STARR, JI ;
RUBENSTEIN, AH .
AMERICAN JOURNAL OF MEDICINE, 1977, 63 (06) :865-869
[44]   ROLE OF GLUCOSE AND INSULIN RESISTANCE IN DEVELOPMENT OF TYPE-2 DIABETES-MELLITUS - RESULTS OF A 25-YEAR FOLLOW-UP-STUDY [J].
MARTIN, BC ;
WARRAM, JH ;
KROLEWSKI, AS ;
BERGMAN, RN ;
SOELDNER, JS ;
KAHN, CR .
LANCET, 1992, 340 (8825) :925-929
[45]   LOCALIZATION OF MODY3 TO A 5-CM REGION OF HUMAN-CHROMOSOME-12 [J].
MENZEL, S ;
YAMAGATA, K ;
TRABB, JB ;
NERUP, J ;
PERMUTT, MA ;
FAJANS, SS ;
MENZEL, R ;
IWASAKI, N ;
OMORI, Y ;
COX, NJ ;
BELL, GI .
DIABETES, 1995, 44 (12) :1408-1413
[46]   ROLE OF REDUCED SUPPRESSION OF GLUCOSE-PRODUCTION AND DIMINISHED EARLY INSULIN RELEASE IN IMPAIRED GLUCOSE-TOLERANCE [J].
MITRAKOU, A ;
KELLEY, D ;
MOKAN, M ;
VENEMAN, T ;
PANGBURN, T ;
REILLY, J ;
GERICH, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (01) :22-29
[47]   INSULIN BINDING IN DIABETES - RELATIONSHIPS WITH PLASMA-INSULIN LEVELS AND INSULIN SENSITIVITY [J].
OLEFSKY, JM ;
REAVEN, GM .
DIABETES, 1977, 26 (07) :680-688
[48]   DECREASED INSULIN BINDING TO LYMPHOCYTES FROM DIABETIC SUBJECTS [J].
OLEFSKY, JM ;
REAVEN, GM .
JOURNAL OF CLINICAL INVESTIGATION, 1974, 54 (06) :1323-1328
[49]   LACK OF CONTROL BY GLUCOSE OF ULTRADIAN INSULIN SECRETORY OSCILLATIONS IN IMPAIRED GLUCOSE-TOLERANCE AND IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS [J].
OMEARA, NM ;
STURIS, J ;
VANCAUTER, E ;
POLONSKY, KS .
JOURNAL OF CLINICAL INVESTIGATION, 1993, 92 (01) :262-271
[50]   IMPAIRED PULSATILE SECRETION OF INSULIN IN RELATIVES OF PATIENTS WITH NON-INSULIN-DEPENDENT DIABETES [J].
ORAHILLY, S ;
TURNER, RC ;
MATTHEWS, DR .
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (19) :1225-1230
12345678