No evidence of vertical transmission of SARS-CoV-2 after induction of labour in an immune-suppressed SARS-CoV-2-positive patient

被引：18

作者：

Grimminck, Koen ^{[1
]}

Santegoets, Lindy Anne Maria ^{[1
]}

Siemens, Frederike Charlotte ^{[1
]}

Fraaij, Pieter Leendert Alex ^{[2
,3
]}

Reiss, Irwin Karl Marcel ^{[4
]}

Schoenmakers, Sam ^{[5
]}

机构：

[1] Reinier de Graaf Gasthuis, Dept Obstet & Gynaecol, Delft, Zuid Holland, Netherlands

[2] Erasmus Med Ctr Sophia, Dept Paediat, Subdiv Infect Dis & Immunol, Rotterdam, Netherlands

[3] Erasmus MC, Dept Virosci, Rotterdam, Netherlands

[4] Erasmus MC, Div Neonatol, Rotterdam, Netherlands

[5] Erasmus MC, Dept Obstet & Gynaecol, Rotterdam, Zuid Holland, Netherlands

来源：

BMJ CASE REPORTS | 2020年 / 13卷 / 06期

关键词：

materno-fetal medicine; pregnancy; pneumonia (infectious disease); infectious diseases; global health;

D O I：

10.1136/bcr-2020-235581

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of a 38+1 weeks pregnant patient (G1P0) with a proven COVID-19 infection, who was planned for induction of labour because of pre-existent hypertension, systemic lupus erythematosus, respiratory problem of coughing and mild dyspnoea without fever during the COVID-19 pandemic in March 2020. To estimate the risk of vertical transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) during labour and delivery, we collected oropharyngeal, vaginal, urinary, placental and neonatal PCRs for SARS-CoV-2 during the period of admission. All PCRs, except for the oropharyngeal, were negative and vertical transmission was not observed. Labour and delivery were uncomplicated and the patient and neonate were discharged the next day. We give a short overview of the known literature about SARS-CoV-2-related infection during pregnancy, delivery and outcome of the neonate.

引用

页数：4

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