A review of mortality due to Clostridium difficile infection

被引：122

作者：

Karas, J. A. ^{[1
]}

Enoch, D. A. ^{[2
]}

Aliyu, S. H. ^{[1
]}

机构：

[1] Addenbrookes Hosp, Hlth Protect Agcy, Clin Microbiol & Publ Hlth Lab, Cambridge CB2 0QQ, England

[2] Peterborough Dist Gen Hosp, Clin Microbiol & Publ Hlth Lab, Peterborough PE3 6JW, Cambs, England

来源：

JOURNAL OF INFECTION | 2010年 / 61卷 / 01期

关键词：

Clostridium difficile; Hospital acquired infection; Nosocomial infections; Pseudomembranous colitis; Mortality; RISK-FACTORS; NOSOCOMIAL INFECTION; LARGE OUTBREAK; DISEASE; DIARRHEA; COLITIS; MANAGEMENT; METRONIDAZOLE; MORBIDITY; HOSPITALS;

D O I：

10.1016/j.jinf.2010.03.025

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In this review we examine published literature to ascertain mortality in relation to Clostridium difficile infection (CDI) and the factors associated with mortality. In the 27 studies that had sufficient data, there were 10975 cases of CDI with great heterogeneity in the methods for reporting mortality. We calculated the overall associated mortality to be at least 5.99% within 3 months of diagnosis. The most important finding is that higher mortality is associated with advanced age, being 13.5% in patients over 80 years. Studies performed after 2000 had a significantly higher mortality than those before this date. We propose minimum standards for reporting mortality in future studies. (c) 2010 The British Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：1 / 8

页数：8

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